Protein Alignment Cyp6u1 and cyp-13A12

DIOPT Version :10

• Sequence 1: NP_610252.3
• Gene: Cyp6u1 / 35608
• FlyBaseID: FBgn0033121
• Length: 488
• Species: Drosophila melanogaster
• Sequence 2: NP_499705.1
• Gene: cyp-13A12 / 184473
• WormBaseID: WBGene00008810
• Length: 518
• Species: Caenorhabditis elegans
• Alignment Length: 556
• Identity: 134/556 - (24%)
• Similarity: 224/556 - (40%)
• Gaps: 134/556 - (24%)

  Fly    12 LGALSVVYALVKFSL---GYWKRRGIL----------------HEKPKFL--------WGNIKGV 49
            |..|:.:..::.|.|   .|||||||.                .|.|.:|        :|.:.|:
 Worm     6 LAILTSIIGVLSFYLWTWSYWKRRGIAGPSGYPILGSALEMLSSENPPYLQLKEWTKQYGKVYGI 70

  Fly    50 VSGKRHAQDALQDIYTAYKGRAPFVGFYACLKPFILALDLKLVHQIIFTDAGHFTSRGLYSNP-S 113
            ..|                           |...::..|..||.::......:|..|.|  || .
 Worm    71 TEG---------------------------LSRTLVISDPDLVQEVFVKQYDNFFGRKL--NPIQ 106

  Fly   114 GEPLSH---NLLQLDGHKWRSLHAKSAEVFTPANMQKLLVRLSQISSRIQRDLGEKS--LQTINI 173
            |:|...   ||....||:|:.|...|:..|:..:::||...:.:.:..:.|.:.:.:  .|.|::
 Worm   107 GDPNKDKRVNLFSSQGHRWKRLRTISSPTFSNNSLRKLKTTVEECAVELLRHIEQHTDGGQPIDL 171

  Fly   174 SELVGAYNTDVMASMAFGLVGQDNVEFAK-----WTRNYWADFRMWQAYLALEFPLIARLLQYKS 233
            .:....:..||:..:|   :||.:.:..|     :.|..:.:.|..........|.|..:|:...
 Worm   172 LDFYQEFTLDVIGRIA---MGQTDSQMFKNPLLPYVRAVFGEPRKGLFLSGSLAPWIGPILRMVM 233

  Fly   234 YAEP--------------ATAYFQKVALSQLQLHRRRDRQPLQTFLQLYSNAE------------ 272
            ::.|              :.|..|:|.|.........|....|.|:.|:.:|:
 Worm   234 FSLPNIVKNPAVHVIRHTSNAVEQRVKLRMADEKAGIDPGEPQDFIDLFLDAKSDDVELENNEDF 298

  Fly   273 --------KPLTDIEIAGQAFGFVLAGLGPLNATLAFCLYELARQPEVQDRTRLEINKALEEHGG 329
                    :.||..||.||.|.|::||......:|::..:.||..|:||.:.:.||::...:  .
 Worm   299 TKAGVKVTRQLTTEEIVGQCFVFLIAGFDTTALSLSYSSFLLATHPKVQKKLQEEIDRECAD--P 361

  Fly   330 QVTPECLRELRYTKQVLNETLRLHTPHPFLLR-----RATK--EFEVPGSVFVIAKGNNVLIPTA 387
            :||.:.|.:|:|.:.|:.||||:: |...|..     ||||  .:|       |.:|.|:|..|.
 Worm   362 EVTFDQLSKLKYMECVIKETLRMY-PLGALANSRCCMRATKIGNYE-------IDEGTNILCDTW 418

  Fly   388 AIHMDPGIY-ENPQRFYPERFEEQARRSRPAAAFLPFGDGLRGCIAARFA--EQQLLVGLVALLR 449
            .:|.|..|: |:.:.|.|||:|...........::|||.|.|.||..|.|  |::||  |..:||
 Worm   419 TLHSDKSIWGEDAEEFKPERWESGDEHFYQKGGYIPFGLGPRQCIGMRLAYMEEKLL--LSHILR 481

  Fly   450 QHRYAPSAETSIPVEYDNRR--------LLLMPKSD 477
            ::......:|.||::....|        |.|.|:.|
 Worm   482 KYTLEVCNKTQIPLKLIGSRTTQPESVWLNLTPRDD 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6u1	NP_610252.3	CYP6-like	69..479	CDD:410679	117/472 (25%)
cyp-13A12	NP_499705.1	CYP3A-like	63..507	CDD:410678	116/487 (24%)