Protein Alignment Cyp6u1 and Cyp3a9

DIOPT Version :9

• Sequence 1: NP_001286149.1
• Gene: Cyp6u1 / 35608
• FlyBaseID: FBgn0033121
• Length: 488
• Species: Drosophila melanogaster
• Sequence 2: NP_671739.2
• Gene: Cyp3a9 / 171352
• RGDID: 708392
• Length: 503
• Species: Rattus norvegicus
• Alignment Length: 519
• Identity: 143/519 - (27%)
• Similarity: 254/519 - (48%)
• Gaps: 53/519 - (10%)

  Fly     1 MDLM----HRTLLTALGALSVVYALVKFSLGYWKRRGILHEKPKFLWGNI----KGVVSGKRHAQ 57
            |||:    ..|.|..:.:|.::|.....|.|.:|:.||...||....|.|    ||.....::..
  Rat     1 MDLIPNFSMETWLLLVISLVLLYLYGTHSHGIFKKLGIPGPKPLPFLGTILAYRKGFWEFDKYCH 65

  Fly    58 DALQDIYTAYKGRAPFVGFYACLKPFILALDLKLVHQIIFTDAGHFTSRGLYSNPSGEPLSHNLL 122
            .....::..|.||.|.:   |...|.|:...|.......||:..:|...|:        |...:.
  Rat    66 KKYGKLWGLYDGRQPVL---AITDPDIIKTVLVKECYSTFTNRRNFGPVGI--------LKKAIS 119

  Fly   123 QLDGHKWRSLHAKSAEVFTPANMQKLLVRLSQISSRIQRDL--GEKSLQTINISELVGAYNTDVM 185
            ..:..:|:.:.|..:..||...::::...::|.:..:.|::  |.:..:..::.::.|||:.||:
  Rat   120 ISEDEEWKRIRALLSPTFTSGKLKEMFPIINQYTDMLVRNMRQGSEEGKPTSMKDIFGAYSMDVI 184

  Fly   186 ASMAFGLVGQDNVEFAKWTRNYWAD-------FRMWQ-AYLALE-FPLIARL---LQYKSYAEPA 238
            .:.:||:    ||:.....::.:.:       |.::. .:|::. ||.:..|   |....:....
  Rat   185 TATSFGV----NVDSLNNPQDPFVEKIKKLLKFDIFDPLFLSVTLFPFLTPLFEALNVSMFPRDV 245

  Fly   239 TAYFQKVALSQLQLHRRRDRQPLQ-TFLQLYSNAE--------KPLTDIEIAGQAFGFVLAGLGP 294
            ..:| |.::.:::.:|.::::..: .||||..|::        |.|:|:||..|:..|:.||...
  Rat   246 IDFF-KTSVERMKENRMKEKEKQRMDFLQLMINSQNSKVKDSHKALSDVEIVAQSVIFIFAGYET 309

  Fly   295 LNATLAFCLYELARQPEVQDRTRLEINKALEEHGGQVTPECLRELRYTKQVLNETLRLHTPHPFL 359
            .::.|:|.||.||..|::|.:.:.||:.|| .:....|.:.|.::.|...|:||||||: |....
  Rat   310 TSSALSFVLYLLAIHPDIQKKLQDEIDAAL-PNKAHATYDTLLQMEYLDMVVNETLRLY-PIAGR 372

  Fly   360 LRRATK-EFEVPGSVFVIAKGNNVLIPTAAIHMDPGIYENPQRFYPERFEEQARRSRPAAAFLPF 423
            |.|..| :.|:.| || |.||..|:|||.|:|.||..:..|:.|.||||.::.:.:.....:|||
  Rat   373 LERVCKTDVEING-VF-IPKGTVVMIPTFALHKDPHYWPEPEEFRPERFSKKNQDNINPYMYLPF 435

  Fly   424 GDGLRGCIAARFAEQQLLVGLVALLRQHRYAPSAETSIPVEYDNRRLLLMPKSDIKLSVERVDK 487
            |:|.|.||..|||...:.|.||.:|:...:.|..||.||::. :::.||.|:..:.|.|...|:
  Rat   436 GNGPRNCIGMRFALMNMKVALVRVLQNFSFQPCKETQIPLKL-SKQGLLQPEKPLLLKVVSRDE 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6u1	NP_001286149.1	p450	38..475	CDD:299894	127/464 (27%)
Cyp3a9	NP_671739.2	p450	39..493	CDD:278495	129/474 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.820