Protein Alignment Cyp6u1 and Cyp3a16

DIOPT Version :9

• Sequence 1: NP_001286149.1
• Gene: Cyp6u1 / 35608
• FlyBaseID: FBgn0033121
• Length: 488
• Species: Drosophila melanogaster
• Sequence 2: NP_031846.2
• Gene: Cyp3a16 / 13114
• MGIID: 106099
• Length: 504
• Species: Mus musculus
• Alignment Length: 524
• Identity: 140/524 - (26%)
• Similarity: 239/524 - (45%)
• Gaps: 72/524 - (13%)

  Fly     1 MDLMHRTLLTALGALSVVYALV----KFSLGYWKRRGILHEKPKFLWGNI----KGVVSGKRHAQ 57
            |:|.....|..|..|:::..|:    ..:.|.:|::||...||....|.:    ||:........
Mouse     1 MNLFSALSLDTLVLLAIILVLLYRYGTCTHGLFKKQGIPGPKPLPFLGTVLNYYKGLWKFDMECY 65

  Fly    58 DALQDIYTAYKGRAPFVGFYACLKPFILALDLKLVHQI-------IFTDAGHFTSRGLYSNPSGE 115
            :.....:..:.|:.|.         |::. |.:.:..:       :||:...|...|:
Mouse    66 EKYGKTWGLFDGQIPL---------FVIT-DPETIKNVLVKECFSVFTNRQDFFPVGI------- 113

  Fly   116 PLSHNLLQLDGHKWRSLHAKSAEVFTPANMQKLLVRLSQ---ISSRIQRDLGEKSLQTINISELV 177
             :|.::......:|:...|..:..||..|::::...:.|   |..:..|...||. :.:.:.:::
Mouse   114 -MSKSISLAKDEEWKRYRALLSPTFTSGNLKEMFPVIEQYGDILVKYLRQEAEKG-KPVAVKDVL 176

  Fly   178 GAYNTDVMASMAFGLVGQDN--------VEFAKWTRNYWAD-FRMWQAYLALEFPL---IARLLQ 230
            |||:.||:.|..|| |..|:        ||.||....:  | |......:|| ||.   |..:|.
Mouse   177 GAYSMDVIISTTFG-VNIDSLNNPEDPFVENAKKVLRF--DYFDPLSLSVAL-FPFLTPIYEMLN 237

  Fly   231 YKSYAEPATAYFQKVA-------LSQLQLHRRRDRQPLQTFLQLYS-----NAEKPLTDIEIAGQ 283
            ...:.:.:..:|:|..       |...|.||   ...:...::.|:     ::.|.|::|||..|
Mouse   238 ICMFPKDSIEFFKKFVDRMTENRLDSKQKHR---VDFIYLMMEAYNKSKDKDSHKALSEIEITAQ 299

  Fly   284 AFGFVLAGLGPLNATLAFCLYELARQPEVQDRTRLEINKALEEHGGQVTPECLRELRYTKQVLNE 348
            :..|:.||....::.|:|.:|.||..|::|.:.:.||::|| .:....|.:.:..:.|...||||
Mouse   300 SIIFIFAGYETTSSILSFTVYSLATHPDIQKKLQEEIDEAL-PNKAPPTYDTVMAMEYLDMVLNE 363

  Fly   349 TLRLHTPHPFLLRRATKEFEVPGSVFVIAKGNNVLIPTAAIHMDPGIYENPQRFYPERFEEQARR 413
            ||||:.....|.|...|:.|:.|  ..|.||:.|:||:..:|.||..:..|:.|.||||.::.:.
Mouse   364 TLRLYPITNRLQRVCKKDVEING--IYIPKGSTVIIPSYVLHHDPQHWPEPEEFQPERFSKENKG 426

  Fly   414 SRPAAAFLPFGDGLRGCIAARFAEQQLLVGLVALLRQHRYAPSAETSIPVEYDNRRLLLMPKSDI 478
            |.....:||||:|.|.||..|||...:.:.|:.:|:...:.|..||.||::. :|.|||.|...|
Mouse   427 SIDPYVYLPFGNGPRNCIGMRFALMNMKLALIKVLQNFSFQPCKETQIPLKL-SRELLLQPVKPI 490

  Fly   479 KLSV 482
            .|.|
Mouse   491 VLKV 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6u1	NP_001286149.1	p450	38..475	CDD:299894	126/474 (27%)
Cyp3a16	NP_031846.2	p450	39..494	CDD:278495	129/484 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.820