Protein Alignment Cyp6u1 and Cyp3a41b

DIOPT Version :10

• Sequence 1: NP_610252.3
• Gene: Cyp6u1 / 35608
• FlyBaseID: FBgn0033121
• Length: 488
• Species: Drosophila melanogaster
• Sequence 2: NP_001098629.1
• Gene: Cyp3a41b / 100041375
• MGIID: 3714859
• Length: 504
• Species: Mus musculus
• Alignment Length: 497
• Identity: 135/497 - (27%)
• Similarity: 225/497 - (45%)
• Gaps: 74/497 - (14%)

  Fly    27 GYWKRRGILHEKPKFLWGNI----KGVVSGKRHAQDALQDIYTAYKGRAPFVGFYACLKPFILAL 87
            |.:|::||...||....|.:    ||:........:.....:..:.|:.|.         |::.
Mouse    31 GLFKKQGIPGPKPLPFLGTVLNYYKGLWKFDMECYEKYGKTWGLFDGQMPL---------FVIT- 85

  Fly    88 DLKLVHQI-------IFTDAGHFTSRGLYSNPSGEPLSHNLLQLDGHKWRSLHAKSAEVFTPANM 145
            |.:::..:       :||:...|...|:.|....       :..| .:|:...|..:..||...:
Mouse    86 DPEMIKNVLVKECFSVFTNRREFGPVGIMSKAIS-------ISKD-EEWKRYRALLSPTFTSGKL 142

  Fly   146 QKLLVRLSQISSRIQRDL---GEKSLQTINISELVGAYNTDVMASMAFGLVGQDN--------VE 199
            :::...:.|....:.:.|   .||. :.:.:.:::|||:.||:.|.:|| |..|:        ||
Mouse   143 KEMFPVIEQYGDILVKYLMQEAEKG-KPVTMKDVLGAYSIDVITSTSFG-VNVDSLNNPEDPFVE 205

  Fly   200 FAKWTRNYWADFRMWQAYLALEFPLIA---RLLQYKSYAEPATAYFQKVA-------LSQLQLHR 254
            .||....  .||.....:..:.||.:.   .:|....:.:.:..:|:|..       |...|.||
Mouse   206 KAKGILR--VDFFDPLVFSVVLFPFLTPVYEMLNICMFPKDSIEFFKKFVNRMKESRLDSKQKHR 268

  Fly   255 RRDRQPLQTFLQLYSNA---------EKPLTDIEIAGQAFGFVLAGLGPLNATLAFCLYELARQP 310
                   ..||||..||         .|.|:|:||..|:..|:.||....::||:|.||.||..|
Mouse   269 -------VDFLQLMMNAHNNSKDKDSHKALSDMEITAQSIVFIFAGYETTSSTLSFTLYCLATHP 326

  Fly   311 EVQDRTRLEINKALEEHGGQVTPECLRELRYTKQVLNETLRLHTPHPFLLRRATKEFEVPGSVFV 375
            ::|.:.:.||::.| .:....|.:.:.|:.|...||||||||:.....|.|...|:.|:.|  ..
Mouse   327 DIQKKLQEEIDETL-PNKAPPTYDTVMEMEYLDMVLNETLRLYPIGNRLERFCKKDVELNG--VY 388

  Fly   376 IAKGNNVLIPTAAIHMDPGIYENPQRFYPERFEEQARRSRPAAAFLPFGDGLRGCIAARFAEQQL 440
            |.||:.|:||:.|:|.||..:..|:.|.||||.::.:.|.....::|||.|.|.||..|||...:
Mouse   389 IPKGSTVMIPSYALHHDPQHWPEPEEFQPERFSKENKGSIDPYLYMPFGIGPRNCIGMRFAFMTM 453

  Fly   441 LVGLVALLRQHRYAPSAETSIPVEYDNRRLLLMPKSDIKLSV 482
            .:.|..:::...:.|..||.||::. :|:.||.|:..|.|.|
Mouse   454 KLALTKVMQNFSFQPCQETQIPLKL-SRQGLLQPEKPIVLKV 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6u1	NP_610252.3	CYP6-like	69..479	CDD:410679	123/446 (28%)
Cyp3a41b	NP_001098629.1	CYP3A	67..493	CDD:410743	124/458 (27%)