Protein Alignment Cyp6u1 and cyp3a5

DIOPT Version :10

• Sequence 1: NP_610252.3
• Gene: Cyp6u1 / 35608
• FlyBaseID: FBgn0033121
• Length: 488
• Species: Drosophila melanogaster
• Sequence 2: XP_012819594.1
• Gene: cyp3a5 / 100037874
• XenbaseID: XB-GENE-5821575
• Length: 510
• Species: Xenopus tropicalis
• Alignment Length: 512
• Identity: 133/512 - (25%)
• Similarity: 232/512 - (45%)
• Gaps: 64/512 - (12%)

  Fly     7 TLLTALGALSVVYALVKFSLGYWKRRGILHEKP-KFLWGNIKGVVSGKRHAQDALQDIYTAYKGR 70
            |||..|..|...||:..:.|  :||.||....| .|:     |...|.||.  .::.....:|..
 Frog    13 TLLVLLLTLLAYYAIWPYKL--FKRYGIPGPTPIPFI-----GTFLGNRHG--LMEFDMECFKKY 68

  Fly    71 APFVGFYACLKPFILALDLKLVHQIIFTDA-GHFTSR---GLYSNPSGEPLSHNLLQLDGHKWRS 131
            ....|.|...||.:..:|..::..|:..:. .:||:|   ||    || ||..::|.....:|:.
 Frog    69 GKVWGIYEGQKPLLAIVDPVIIKSIMVKECYTNFTNRRDFGL----SG-PLKSSVLISKDEQWKR 128

  Fly   132 LHAKSAEVFTPANMQKLLVRLSQISSRIQRDLGEK--SLQTINISELVGAYNTDVMASMAFGL-- 192
            :....:..||...::::...::.....:.:::.:|  :.:.:::..:.|:|:.|::.|.:|.:
 Frog   129 IRTVLSPTFTSGKLKQMFPLMNHYGELLVKNIHKKINNKEPLDMKHIFGSYSMDIVLSTSFSVNV 193

  Fly   193 --VGQDNVEFAKWTRNYWADFRMWQAYLALEF--PLIARLLQYKSYA--EPATAYFQKVALSQLQ 251
              :...|..|....||.:. |..:.....:..  |.:..||...::.  ......|.|.|::.::
 Frog   194 DSMNNPNDPFVTNARNLFT-FSFFNPLFLISILCPFLVPLLDKMNFCFLSLKILNFFKDAVASIK 257

  Fly   252 LHRRR----DRQPLQTFLQLYSNAE---------------KPLTDIEIAGQAFGFVLAGLGPLNA 297
            ..|::    ||   ..||||..:|:               |.|:|.||..|:..|::||....:.
 Frog   258 KKRQKGTHEDR---VDFLQLMVDAQSNEGKSVPEEEKHGYKELSDTEILAQSLIFIMAGYETTST 319

  Fly   298 TLAFCLYELARQPEVQDRTRLEINKALEEHGGQVTPECLRELRYTKQVLNETLRLHTPHPFLLRR 362
            ||.|..|.:|..|:||.:...||: ||..:....|.:.|.::.|...|:||:||:..|...:.|.
 Frog   320 TLMFLAYNIATHPDVQRKLEEEID-ALLPNKAPPTYDALMKMEYMDMVINESLRMFPPAIRIDRV 383

  Fly   363 ATKEFEVPGSVFVIAKGNNVLIPTAAIHMDPGIYENPQRFYPERFEEQARRSRPAAAFLPFGDGL 427
            ..|..|:.|  ..|..|..:::|..|:|::|.|:..|:.|.||||.::.::::....|||||.|.
 Frog   384 CKKTMEING--VTIPAGVVIVVPLFALHLNPEIWPEPEEFQPERFSKENQKNQDPYNFLPFGVGP 446

  Fly   428 RGCIAARFAEQQLLVGLVALLRQHRYAPSAETSIPVEYDNRRLL---------LMPK 475
            |.||..|||...:.|.|..||:..|.....:|.:|::...:..|         |:||
 Frog   447 RNCIGMRFALVNMKVALTILLQNFRLETCKDTPVPLKICTKGYLKPTKPIILNLIPK 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6u1	NP_610252.3	CYP6-like	69..479	CDD:410679	114/449 (25%)
cyp3a5	XP_012819594.1	cytochrome_P450	67..498	CDD:477761	111/442 (25%)