DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42De and Serpina9

DIOPT Version :9

Sequence 1:	NP_610246.3	Gene:	Spn42De / 35602	FlyBaseID:	FBgn0033115	Length:	404	Species:	Drosophila melanogaster
Sequence 2:	NP_001348839.1	Gene:	Serpina9 / 71907	MGIID:	1919157	Length:	418	Species:	Mus musculus

Alignment Length:	415	Identity:	123/415 - (29%)
Similarity:	210/415 - (50%)	Gaps:	33/415 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LLLLQGL-------------NLAMANTLNYSKSPAGE-----AQFASQLFGQLAKSQSGRNIVFS 55
            :|||.|.             |...::..:..|:||.:     .:|:..|:.:||:...|:||:||
Mouse     9 VLLLVGFCAPIFCMLSSNPYNQESSHLPSMKKNPASQVSPSNTRFSFLLYQRLAQENPGQNILFS 73

  Fly    56 PSSIRTGLALAYLGAEGSTADELKLGLGLEGAGKTEVAEKLD-QLLAKGQWEKASGDEDVPKLKY 119
            |.||.|.||:..|||..:|..::...||......:|....:. :.|.:...:...|.|    |:.
Mouse    74 PVSISTSLAMLSLGARSATKTQILRTLGFNFTWVSEPTIHMGFEYLVRSLNKCHQGRE----LRM 134

  Fly   120 ANRIFVTQRFKLTQTYQDLVSKNFAAAAENVNFTQKADTAKHINSWVEEQTHQQIKDLIAPESLD 184
            .:.:|:.:..:|..|:.|.|.|.:.|...:.:|:..|.....|||:||::|..::.|:|  :.||
Mouse   135 GSVLFIRKELQLQATFLDRVKKLYGAKVFSEDFSNAATAQAQINSYVEKETKGKVVDVI--QDLD 197

  Fly   185 ADTSAILVNAIYFKADWQSSFPDYATYAS-DFVNHGGRKVSVDTMSQEDYFRFGELTELKAKVVE 248
            :.|:.:|||.|:|||:|...|....|..| .|:...|..|.|..|.|.:.|.||...||...:::
Mouse   198 SQTAMVLVNHIFFKANWTQPFSTANTNKSFPFLLSKGTTVHVPMMHQTESFAFGVDKELGCSILQ 262

  Fly   249 LPYTGTDIVFLIILPQEEQGLAIVEEKLMGIDLNEISSQLRRRKVRVQLPKFKFEFDVPLQAALE 313
            :.|.| |.|...:||.:.: :..:|:.|....|.:.|..|::|.::|.:|||.......|:..|.
Mouse   263 MDYRG-DAVAFFVLPGKGK-MRQLEKSLSARRLRKWSRSLQKRWIKVFIPKFSISASYNLETILP 325

  Fly   314 ELGIKKLFSPGANLSSLYQGSEPLRISEVKHKAIIEVNEKGTTASGATFIKVSVESLTIGEEVFE 378
            ::||:..|:..|:.|.:.: :..|::|:..|||:::|:|:||.|:.||..|:.|.|......:..
Mouse   326 KMGIRDAFNSNADFSGITK-THFLQVSKAAHKAVLDVSEEGTEAAAATTTKLIVRSRDTPSSIIA 389

  Fly   379 FIADHPFFFAI--KDAQNTLFLGHV 401
            |  ..||...:  |:.::.||||.|
Mouse   390 F--KEPFLILLLDKNTESVLFLGKV 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42De	NP_610246.3	SERPIN	31..401	CDD:238101	114/378 (30%)
Serpina9	NP_001348839.1	alpha-1-antitrypsin_like	49..412	CDD:239011	114/373 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S6342
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.970