Protein Alignment Spn42De and SERPING1

DIOPT Version :9

• Sequence 1: NP_610246.3
• Gene: Spn42De / 35602
• FlyBaseID: FBgn0033115
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: NP_000053.2
• Gene: SERPING1 / 710
• HGNCID: 1228
• Length: 500
• Species: Homo sapiens
• Alignment Length: 384
• Identity: 102/384 - (26%)
• Similarity: 177/384 - (46%)
• Gaps: 44/384 - (11%)

  Fly    31 GEA--QFASQL---FGQLAKSQSGRNIVFSPSSIRTGLALAYLGAEGSTADELKLGLGLEGAGKT 90
            |:|  .|:.:|   |..:.|.::  |:.|||.||.:.|....|||..:|...|:..|... ...|
Human   143 GDALVDFSLKLYHAFSAMKKVET--NMAFSPFSIASLLTQVLLGAGENTKTNLESILSYP-KDFT 204

  Fly    91 EVAEKLDQLLAKGQWEKASGDEDVPKLKYANRIFVTQRFKLTQTYQDLVSKNFAAAAENVNFTQK 155
            .|.:.|.....||             :...::||.:....:..|:.: .|:...:::..|.....
Human   205 CVHQALKGFTTKG-------------VTSVSQIFHSPDLAIRDTFVN-ASRTLYSSSPRVLSNNS 255

  Fly   156 ADTAKHINSWVEEQTHQQIKDLIAPESLDADTSAILVNAIYFKADWQSSFPDYATYASDFVNHGG 220
            ....:.||:||.:.|:.:|..|:  :||.:||..:|:||||..|.|:::|....|....| :...
Human   256 DANLELINTWVAKNTNNKISRLL--DSLPSDTRLVLLNAIYLSAKWKTTFDPKKTRMEPF-HFKN 317

  Fly   221 RKVSVDTMSQEDY--FRFGELTELKAKVVELPYTGTDIVFLIILPQE-EQGLAIVEEKLMGIDLN 282
            ..:.|..|:.:.|  ..|.:.| |||||.:|..: .::..:|::||. :..|..:|:.|......
Human   318 SVIKVPMMNSKKYPVAHFIDQT-LKAKVGQLQLS-HNLSLVILVPQNLKHRLEDMEQALSPSVFK 380

  Fly   283 EISSQLRRRKVR---VQLPKFKFEFDVPLQAALEELGIKKLFSPGANLSSLYQGSEPLRISEVKH 344
            .|..:|...|.:   :.||:.|......:.:.:|:|.... ||...||..|.:..: |::|.::|
Human   381 AIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFFD-FSYDLNLCGLTEDPD-LQVSAMQH 443

  Fly   345 KAIIEVNEKGTTASGATFIKVSVESLTIGEEVFEFIADHPFFFAIKDAQN--TLFLGHV 401
            :.::|:.|.|..|:.|:.|.|:...|     |||  ...||.|.:.|.|:  .:|:|.|
Human   444 QTVLELTETGVEAAAASAISVARTLL-----VFE--VQQPFLFVLWDQQHKFPVFMGRV 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn42De	NP_610246.3	SERPIN	31..401	CDD:238101	101/382 (26%)
SERPING1	NP_000053.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..43
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	65..118
		7 X 4 AA tandem repeats of [QE]-P-T-[TQ]	85..119
		C1_inh	145..495	CDD:239005	100/380 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010