DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42De and serpine3

DIOPT Version :9

Sequence 1:	NP_610246.3	Gene:	Spn42De / 35602	FlyBaseID:	FBgn0033115	Length:	404	Species:	Drosophila melanogaster
Sequence 2:	NP_001116709.1	Gene:	serpine3 / 556612	ZFINID:	ZDB-GENE-050309-223	Length:	417	Species:	Danio rerio

Alignment Length:	404	Identity:	107/404 - (26%)
Similarity:	185/404 - (45%)	Gaps:	35/404 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 MANTLNYSKSPAGEAQFASQLFGQLAKSQSGRNIVFSPSSIRTGLALAYLGAEGSTADELKLGLG 83
            :||::..|.......||...|:..|.::::..|::.||:|:...|.|..|||.|:|..:|:   |
Zfish    21 VANSVLSSSFSDLHTQFGISLYQTLTETENKSNLIVSPASVSLCLGLLQLGARGNTLVQLE---G 82

  Fly    84 LEGAGKTEVAEKLDQLLAKGQWEKASGDEDVPKLKYANRIFVTQRFKLTQTYQDLVSKNFAAAAE 148
            ..|....:|  ::..:|::.|.:.|:..|.: :|:.||.:|:....||...:..........:..
Zfish    83 TLGYDVNDV--RVQNILSRPQGDLANSSEGL-RLQLANALFIQTGVKLLPEFTQHALGWGNTSLL 144

  Fly   149 NVNFTQKADTAKHINSWVEEQT----HQQIKDLIAPESLDADTSA--------ILVNAIYFKADW 201
            :|||:....|...:..|...|:    |.|.::.:...|.:.:.:.        .||:.:.|...|
Zfish   145 SVNFSNPNHTHSRLQQWAHYQSKADDHLQTREELHHSSGEEEEATRQDHLLYMALVSTLVFHGAW 209

  Fly   202 QSSFPDYATYASDFVNHGGRKVSVDTMSQEDYFRFGEL---TELKAKVVELPYTGTDIVFLIILP 263
            |..|....|....|....|..|.|..|.|......|..   :|.:..|:||||....:..|:.||
Zfish   210 QKQFLFTETQNLPFTFSDGSTVKVPMMYQSSEVNIGHFRLPSEQEYTVLELPYLDHSLRLLVALP 274

  Fly   264 QEEQ-GLAIVEEKLMGIDLNEISSQLRRRKVRVQLPKFKFEFDVPLQAALEELGIKKLFSPGANL 327
            .:.: .|:.:|:::....:....:.|||.|:.:.||:||.:..:.|:..|:.||:..:|||.|..
Zfish   275 SDRKTPLSQLEKQITARAVGLWDTGLRRTKMDIFLPRFKMQSKINLKPVLQSLGVSDIFSPSAAD 339

  Fly   328 SSLYQGSEPLRISEVKHKAIIEVNEKGTTASGAT---FIKVSVESLTIGEEVFEFIADHPFFFAI 389
            ......::.:.:||..|:|.|||.|.||.|:.||   .:|.|..::        |.||.||.|.:
Zfish   340 FRGISDTDGIFVSEAFHEARIEVTEAGTKAASATAMVLLKRSRSAV--------FKADRPFLFIL 396

  Fly   390 KDAQ--NTLFLGHV 401
            :...  :.||:|.|
Zfish   397 RQISTGSLLFIGRV 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42De	NP_610246.3	SERPIN	31..401	CDD:238101	103/390 (26%)
serpine3	NP_001116709.1	Serpin	35..413	CDD:278507	104/390 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.020