Protein Alignment Spn42De and SERPINB8

DIOPT Version :9

• Sequence 1: NP_610246.3
• Gene: Spn42De / 35602
• FlyBaseID: FBgn0033115
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: NP_001353127.1
• Gene: SERPINB8 / 5271
• HGNCID: 8952
• Length: 374
• Species: Homo sapiens
• Alignment Length: 374
• Identity: 120/374 - (32%)
• Similarity: 190/374 - (50%)
• Gaps: 18/374 - (4%)

  Fly    35 FASQLFGQLAKSQSGRNIVFSPSSIRTGLALAYLGAEGSTADELKLGLGLEGAGKTEVAEKLDQL 99
            ||..||..|.:..:.||:.|||.||.:.||:.::||:||||.::...|.|...|  ::......|
Human    11 FAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCLYKDG--DIHRGFQSL 73

  Fly   100 LAKGQWEKASGDEDVPKLKYANRIFVTQRFKLTQTYQDLVSKNFAAAAENVNFTQKADTA-KHIN 163
            |::   ...:|.:.:  |:.|||:|..:.......:::...|.:.|..|.::|.:..:.. ||||
Human    74 LSE---VNRTGTQYL--LRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTEECRKHIN 133

  Fly   164 SWVEEQTHQQIKDLIAPESLDADTSAILVNAIYFKADWQSSFPDYATYASDFVNHGGRKVSVDTM 228
            .||.|:|..:|.:::...::|..|..:||||||||..|...|....|....|..:..:| :|..|
Human   134 DWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGMLFKTNEEKK-TVQMM 197

  Fly   229 SQEDYFRFGELTELKAKVVELPYTGTDIVFLIILPQEEQGLAIVEEKLMGIDLN--EISSQLRRR 291
            .:|..|:.|...|:..:|:||||...::..:|:||.:...||:||:.|......  ..|.:|.:.
Human   198 FKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLAVVEKALTYEKFKAWTNSEKLTKS 262

  Fly   292 KVRVQLPKFKFEFDVPLQAALEELGIKKLFSPG-ANLSSLYQGSEPLRISEVKHKAIIEVNEKGT 355
            ||:|.||:.|.|....|:..|..||:...|... |:.|.: ...:.:.:|:|.||..:||||:||
Human   263 KVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFSGM-STEKNVPLSKVAHKCFVEVNEEGT 326

  Fly   356 TASGATFIKVSVESLTIGEEVFEFIADHPFFFAIKDAQNT--LFLGHVS 402
            .|:.||.:   |.:.........|.|||||.|.|:..:..  ||.|..|
Human   327 EAAAATAV---VRNSRCSRMEPRFCADHPFLFFIRHHKTNCILFCGRFS 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn42De	NP_610246.3	SERPIN	31..401	CDD:238101	119/371 (32%)
SERPINB8	NP_001353127.1	SERPIN	4..374	CDD:320777	120/374 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	1	1.000	-	-		mtm8652
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.930