Protein Alignment Spn42De and SERPINB6

DIOPT Version :10

• Sequence 1: NP_610246.3
• Gene: Spn42De / 35602
• FlyBaseID: FBgn0033115
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: XP_011512974.1
• Gene: SERPINB6 / 5269
• HGNCID: 8950
• Length: 454
• Species: Homo sapiens
• Alignment Length: 376
• Identity: 118/376 - (31%)
• Similarity: 193/376 - (51%)
• Gaps: 20/376 - (5%)

  Fly    35 FASQLFGQLAKSQSGRNIVFSPSSIRTGLALAYLGAEGSTADELK--LGLGLEGAGKTEVAEKLD 97
            ||..|...|.|..| :|:.|||.|:...||:.|:||:|:||.::.  |.....|.| .::.:...
Human    89 FALNLLKTLGKDNS-KNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSFNKSGGG-GDIHQGFQ 151

  Fly    98 QLLAKGQWEKASGDEDVPKLKYANRIFVTQRFKLTQTYQDLVSKNFAAAAENVNFTQKAD-TAKH 161
            .||.:   ...:|.:.:  |:.|||:|..:......:::|...|.:.|..|.::|....: :.||
Human   152 SLLTE---VNKTGTQYL--LRMANRLFGEKSCDFLSSFRDSCQKFYQAEMEELDFISAVEKSRKH 211

  Fly   162 INSWVEEQTHQQIKDLIAPESLDADTSAILVNAIYFKADWQSSFPDYATYASDFVNHGGRKVSVD 226
            ||:||.|:|..:|.:|::|.|:|..|..:||||:||:.:|...|....|....|......:..|.
Human   212 INTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDKENTEERLFKVSKNEEKPVQ 276

  Fly   227 TMSQEDYFRFGELTELKAKVVELPYTGTDIVFLIILPQEEQGLAIVEEKLMGIDLNEIS--SQLR 289
            .|.::..|:...:.|:..:::.|||.|.::..:|:||.|...|..||::|......|.:  ..:.
Human   277 MMFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPDETTDLRTVEKELTYEKFVEWTRLDMMD 341

  Fly   290 RRKVRVQLPKFKFEFDVPLQAALEELGIKKLFSPG-ANLSSLYQGSEPLRISEVKHKAIIEVNEK 353
            ..:|.|.||:||.|....:::.|..||:...|..| |:.|.:.|  ..|.:|:|.||:.:||||:
Human   342 EEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGKADFSGMSQ--TDLSLSKVVHKSFVEVNEE 404

  Fly   354 GTTASGATFIKVSVESLTIGEEVFEFIADHPFFFAIKDAQNT--LFLGHVS 402
            ||.|:.||   .::..:.....|..|.|||||.|.|:.::..  ||.|..|
Human   405 GTEAAAAT---AAIMMMRCARFVPRFCADHPFLFFIQHSKTNGILFCGRFS 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn42De	NP_610246.3	serpin42Dd-like_insects	30..403	CDD:381070	118/376 (31%)
SERPINB6	XP_011512974.1	serpinB6_CAP	79..454	CDD:381031	118/376 (31%)