Protein Alignment Spn42De and SERPINA4

DIOPT Version :9

• Sequence 1: NP_610246.3
• Gene: Spn42De / 35602
• FlyBaseID: FBgn0033115
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: NP_001275961.1
• Gene: SERPINA4 / 5267
• HGNCID: 8948
• Length: 464
• Species: Homo sapiens
• Alignment Length: 439
• Identity: 125/439 - (28%)
• Similarity: 184/439 - (41%)
• Gaps: 71/439 - (16%)

  Fly     9 LLLLQGLNLAM--------------ANTLNYSKSPAGE-----------AQFASQLFGQLAKSQS 48
            ||||.|| ||:              :|:.:......||           |.||.:.:..:|....
Human    45 LLLLVGL-LALSHGQLHVEHDGESCSNSSHQQILETGEGSPSLKIAPANADFAFRFYYLIASETP 108

  Fly    49 GRNIVFSPSSIRTGLALAYLGAEGSTADELKLGLGLEGAGKTEVAEK---------LDQLLAKGQ 104
            |:||.|||.||....|:..|||...:..::..|||.   ..||::|.         |..|...|.
Human   109 GKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGF---NLTELSESDVHRGFQHLLHTLNLPGH 170

  Fly   105 WEKASGDEDVPKLKYANRIFVTQRFKLTQTYQDLVSKNFAAAAENVNFTQKADTAKHINSWVEEQ 169
                 |.|    .:..:.:|::...|....:.:.....:.|...:.||.....|.:.||..|:::
Human   171 -----GLE----TRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQLINDHVKKE 226

  Fly   170 THQQIKDLIAPESLDADTSAILVNAIYFKADWQSSFPDYATYASDFVNHGGRKVSVDTMSQED-- 232
            |..:|.||::  .|..|...:|||.|||||.|:..|....|...||.......|.|..|.|:.
Human   227 TRGKIVDLVS--ELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTTVRVPMMLQDQEH 289

  Fly   233 ----YFRFGELTELKAKVVELPYTGTDIVFLIILPQEEQGLAIVEEKLMGIDLNEISSQLRRR-- 291
                :.|:     |...|:.:.|.|...|| .|||.:.: :..:||.|....|...::.||:|
Human   290 HWYLHDRY-----LPCSVLRMDYKGDATVF-FILPNQGK-MREIEEVLTPEMLMRWNNLLRKRNF 347

  Fly   292 --KVRVQLPKFKFEFDVPLQAALEELGIKKLFSPGANLSSLYQGSEPLRISEVKHKAIIEVNEKG 354
              |:.:.||||.......|...|..||...|||..|:||.:.: .:.|..|:..|||.::|:|.|
Human   348 YKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITK-QQKLEASKSFHKATLDVDEAG 411

  Fly   355 TTASGATFIKVSVESLTIGEEVFEFIADHPFFFAI--KDAQNTLFLGHV 401
            |.|:.||...:...|......:..|  :.||...|  ...|:.||||.|
Human   412 TEAAAATSFAIKFFSAQTNRHILRF--NRPFLVVIFSTSTQSVLFLGKV 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn42De	NP_610246.3	SERPIN	31..401	CDD:238101	115/401 (29%)
SERPINA4	NP_001275961.1	alpha-1-antitrypsin_like	91..458	CDD:239011	113/390 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	4.020