DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42De and serpinb1

DIOPT Version :9

Sequence 1:	NP_610246.3	Gene:	Spn42De / 35602	FlyBaseID:	FBgn0033115	Length:	404	Species:	Drosophila melanogaster
Sequence 2:	NP_001002653.1	Gene:	serpinb1 / 436926	ZFINID:	ZDB-GENE-040718-400	Length:	380	Species:	Danio rerio

Alignment Length:	394	Identity:	126/394 - (31%)
Similarity:	193/394 - (48%)	Gaps:	34/394 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 LAMANTLNYSKSPAGEAQFASQLFGQLAKSQSGRNIVFSPSSIRTGLALAYLGAEGSTADELKLG 81
            ::.||:|           ||..|:..|:.|.:..||.|||.||...|::.||||.|.||.|::..
Zfish     4 VSRANSL-----------FALDLYRALSASSAEGNIFFSPLSISAALSMVYLGARGDTAGEMEKV 57

  Fly    82 LGLEGAGKTEVAEKLDQLLAKGQWEKASGDEDVPKLKYANRIFVTQRFKLTQTYQDLVSKNFAAA 146
            |.....  ::|....:.|::......||     ..|:.|||::..:.|.....|.......:.|.
Zfish    58 LSFSSV--SDVHSHFESLISSINSPSAS-----YILRLANRLYGEKTFSFLPEYLSSSLNLYHAD 115

  Fly   147 AENVNFTQKADTAKH-INSWVEEQTHQQIKDLIAPESLDADTSAILVNAIYFKADWQSSFPDYAT 210
            .:.|:|...::.::. ||.||||||..:|:||:.|..:...|...||||||||.:|...|....|
Zfish   116 LQAVDFIGASEQSRQLINKWVEEQTENKIRDLLKPGMVTGMTRLALVNAIYFKGNWLQRFNAQDT 180

  Fly   211 YASDFVNHGGRKVSVDTMSQEDYFRFGELTELKAKVVELPYTGTDIVFLIILPQEEQG----LAI 271
            ....|..:......|..|.|:..|.|..:.:.:.:|:||||...::..||:||:|.|.    |..
Zfish   181 KEMPFKINQKENRPVQMMYQKKKFPFNYIYDHRVQVLELPYVKEELSMLILLPEETQDGSDPLLK 245

  Fly   272 VEEKLMGIDLNEISSQLR---RRKVRVQLPKFKFEFDVPLQAALEELGIKKLFSPG-ANLSSLYQ 332
            :|.:|....|:|.:::..   :..:.|.||:||.|.:..|...|..:|:..:|..| |:|:.: .
Zfish   246 LESELTIDKLHEWTNRNNMDTQTDIIVHLPRFKLEIESSLVEILMGMGMSSVFQEGKADLTGM-T 309

  Fly   333 GSEPLRISEVKHKAIIEVNEKGTTASGATFIKVSVESLTIGEEVFEFIADHPFFFAIK--DAQNT 395
            |...|.:|.|.|||.::|||:||.|:.||  ...|....:.||  .|:|||||.|.|:  ...:.
Zfish   310 GHGGLFLSAVAHKAFVDVNEEGTEAAAAT--AAIVAFCMLREE--HFMADHPFLFYIRHNPTNSI 370

  Fly   396 LFLG 399
            ||.|
Zfish   371 LFFG 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42De	NP_610246.3	SERPIN	31..401	CDD:238101	123/380 (32%)
serpinb1	NP_001002653.1	SERPIN	5..379	CDD:294093	126/393 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	1	1.000	-	-		mtm8430
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.830