DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42De and Serpinb6b

DIOPT Version :9

Sequence 1:	NP_610246.3	Gene:	Spn42De / 35602	FlyBaseID:	FBgn0033115	Length:	404	Species:	Drosophila melanogaster
Sequence 2:	XP_038951899.1	Gene:	Serpinb6b / 364705	RGDID:	1310452	Length:	388	Species:	Rattus norvegicus

Alignment Length:	396	Identity:	128/396 - (32%)
Similarity:	209/396 - (52%)	Gaps:	34/396 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 PAGEAQ--FASQLFGQLAKSQSGRNIVFSPSSIRTGLALAYLGAEGSTADELKLGLGLE---GAG 88
            |..||.  ||..|...|.: .|.:|::|||.||.:|||:.::||:|:||.::...|.|:   |.|
  Rat     3 PLLEANGTFAFNLLKTLGE-DSSKNVLFSPLSISSGLAMVFMGAKGTTAHQMIQALSLDKCSGRG 66

  Fly    89 KTEVAEKLDQLLAKGQWEKASGDEDVPKLKYANRIFVTQRFKLTQTYQDLVSKNFAAAAENVNFT 153
            ..:|.:....||||   ...:|.:.:  ||.|||:|..:.|.:..:::|...|.:.|..|.::|.
  Rat    67 SRDVHQGFQSLLAK---VNKTGTQYL--LKTANRLFGEKTFDILASFKDACRKFYEAEMEELDFK 126

  Fly   154 QKADTAK-HINSWVEEQTHQQ-----------IKDLIAPESLDADTSAILVNAIYFKADWQSSFP 206
            ...:.:: |||:||.::|..|           |.:|::..|::|:|..:||||||||.:|:..|.
  Rat   127 GAPEQSRQHINTWVAKKTEGQSISLNWNSQKKITELLSSGSVNANTPLVLVNAIYFKGNWKKQFN 191

  Fly   207 DYATYASDFVNHGGRKVSVDTMSQEDYFRFGELTELKAKVVELPYTGTDIVFLIILPQEEQGLAI 271
            ...|....|......:..|..|.::..|:...:.|:...::.|||.|.::..:|:||.|...|.:
  Rat   192 KEDTQEMPFKVTKNEEKPVKMMFKKSTFKMTYVEEISTTILLLPYVGNELNMIIMLPDEHIELRM 256

  Fly   272 VEEKLMGIDLNEISS--QLRRRKVRVQLPKFKFEFDVPLQAALEELGIKKLFSPG-ANLSSLYQG 333
            ||:::......|.:|  ::..|:|.|.|||||.|.:..::..|..||:...|..| |:.|.: ..
  Rat   257 VEKEITYKKFIEWTSLDKMEEREVEVFLPKFKLEENHDMKDVLHRLGMTDAFEQGMADFSGI-AS 320

  Fly   334 SEPLRISEVKHKAIIEVNEKGTTASGATFIKVSVESLTIGEEVFEFIADHPFFFAIKDAQNT--L 396
            .|.|.:|:|.||:.:||||:||.|:.||...|:...:     |..|.|:|||.|.|:.::..  :
  Rat   321 KEGLFLSKVIHKSFVEVNEEGTEAAAATAANVTFRCM-----VPYFCANHPFLFFIQHSRTNGIV 380

  Fly   397 FLGHVS 402
            |.|..|
  Rat   381 FCGRFS 386

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42De	NP_610246.3	SERPIN	31..401	CDD:238101	126/391 (32%)
Serpinb6b	XP_038951899.1	serpin	1..388	CDD:422956	128/396 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.730