DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Spn42De and serpind1

DIOPT Version :9

Sequence 1:	NP_610246.3	Gene:	Spn42De / 35602	FlyBaseID:	FBgn0033115	Length:	404	Species:	Drosophila melanogaster
Sequence 2:	NP_878300.1	Gene:	serpind1 / 359841	ZFINID:	ZDB-GENE-030711-2	Length:	507	Species:	Danio rerio

Alignment Length:	406	Identity:	102/406 - (25%)
Similarity:	187/406 - (46%)	Gaps:	39/406 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LLLLQG-LNLAMANTLNYSKSPAGEAQFASQLFGQLA-KSQSGRNIVFSPSSIRTGLALAYLGAE 71
            |.|..| ..|...|.:|        |:|..:|:.:|. :.....||:.:|..|...:.:..||..
Zfish   122 LRLFHGQTRLQRINVVN--------ARFGFRLYRKLRNRLNQTDNILLAPVGISIAMGMMGLGVG 178

  Fly    72 GSTADELKLGLGL------EGAGKTEVAEKLDQLLAKGQWEKASGDEDVPKLKYANRIFVTQRFK 130
            .:|.::|...:|.      ..........||.:.|....:.:..|    ..|:..|.::|.:..:
Zfish   179 PNTQEQLFQTVGFAEFVNASNHYDNSTVHKLFRKLTHRLFRRNFG----YTLRSVNDLYVKRNVQ 239

  Fly   131 LTQTYQDLVSKNFAAAAENVNFTQKADTAKHINSWVEEQTHQQIKDLIAPESLDADTSAILVNAI 195
            :..:::......:.|..::|:|...|...| .|..:::.|...||:.:  :|:|.:.:.:|:|.:
Zfish   240 IQDSFRADAKTYYFAEPQSVDFADPAFLVK-ANQRIQKITKGLIKEPL--KSVDPNMAVMLLNYL 301

  Fly   196 YFKADWQSSFPDYATYASDFVNHGGRKVSVDTMSQEDYFRFGELTELKAKVVELPYTGTDIVFLI 260
            |||..|:..||...|:...|..:..::|.|..|..:..:......||...:::|||.| :|..||
Zfish   302 YFKGTWEQKFPKELTHHRQFRVNEKKQVRVLMMQNKGSYLAAADHELNCDILQLPYAG-NISMLI 365

  Fly   261 ILPQEEQGLAIVEEKLMGIDLNEISSQLRRRKVRVQLPKFKFEFDVPLQAALEELGIKKLFSPGA 325
            .:||:..|:..:|:::....:|:..|.:..|...|..|:||.|.:..|...|:|:|:..:|:...
Zfish   366 AVPQKLSGMRSLEQEISPTLVNKWLSNMTNRTREVVFPRFKLEQNYDLIEHLKEMGMTDIFTEKG 430

  Fly   326 NLSSLYQGSEPLRISEVKHKAIIEVNEKGTTASGAT---FIKVSVESLTIGEEVFEFIADHPFFF 387
            :.|.:  .||.:.|:..||:..|.|||:||.|:..|   |:.:|.::        .||.|.||.|
Zfish   431 DFSPM--TSEKVIINWFKHQGSITVNEEGTEAAAMTHIGFMPLSTQT--------RFIVDRPFLF 485

  Fly   388 AIKDAQN--TLFLGHV 401
            .|.:.:.  .:|:|.|
Zfish   486 LIYEHRTGCVVFMGRV 501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42De	NP_610246.3	SERPIN	31..401	CDD:238101	95/381 (25%)
serpind1	NP_878300.1	HCII	61..505	CDD:239002	102/406 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.110