DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42De and LOC299277

DIOPT Version :9

Sequence 1:	NP_610246.3	Gene:	Spn42De / 35602	FlyBaseID:	FBgn0033115	Length:	404	Species:	Drosophila melanogaster
Sequence 2:	XP_008763124.2	Gene:	LOC299277 / 299277	RGDID:	1595900	Length:	420	Species:	Rattus norvegicus

Alignment Length:	395	Identity:	109/395 - (27%)
Similarity:	176/395 - (44%)	Gaps:	49/395 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 LAMANTLNYSKSPAGEAQFASQLFGQLAKSQSGRNIVFSPSSIRTGLALAYLGAEGSTADELKLG 81
            ||..||           .||..|:.:||.....:||.|||.||...||...|||:|:|..|:..|
  Rat    47 LASINT-----------DFAFSLYKELALKNPNKNIAFSPLSISAALASLSLGAKGNTLQEILEG 100

  Fly    82 LGLEGAGKTEV---------AEKLDQLLAKGQWEKASGDEDVPKLKYANRIFVTQRFKLTQTYQD 137
            |.......||:         .::|.|...:||            :..||.:||.:..::...:::
  Rat   101 LKFNLTETTEIDIHQNYRDLLQRLSQPGGQGQ------------ISRANLLFVEKHLQILNGFKE 153

  Fly   138 LVSKNFAAAAENVNFTQKADTAKHINSWVEEQTHQQIKDLIAPESLDADTSAILVNAIYFKADWQ 202
            .....:.......:|.|..:..|.||.:|..|:..:||:::.  .|:..||.:::|.:.|...|.
  Rat   154 KAKALYQTEVFATDFQQTCEARKFINDYVMIQSQGKIKEMVT--ELEERTSIVMLNFLLFTGQWS 216

  Fly   203 SSFPDYATYASDFVNHGGRKVSVDTMSQED----YFRFGELTELKAKVVELPYTGTDIVFLIILP 263
            ..|....|:...|:....|.|.|..|..||    || :.|  |||..||||.|.|.... :.|||
  Rat   217 VPFDPDDTFMGKFILDSRRPVKVLMMKTEDLTTPYF-WDE--ELKCTVVELNYKGHGKA-MFILP 277

  Fly   264 QEEQG-LAIVEEKLMGIDLNEISSQLRRRKV-RVQLPKFKFEFDVPLQAALEELGIKKLFSPGAN 326
              :|| :..||..|....|.:.:..|:.|.: .:.||||.......|:..|.||||..:|:..|:
  Rat   278 --DQGKMEQVEASLHPGTLRKWTDSLKPRIIDELHLPKFSLSKTYKLENILPELGIMDVFNTQAD 340

  Fly   327 LSSLYQGSEPLRISEVKHKAIIEVNEKGTTASGATFIKVSVESLTIGEEVFEFIADHPFFFAIKD 391
            ||.: .|::.:|:|::.|..::.:.|.||.|...|.::.:.....:.:....|:  ..|.:.:.:
  Rat   341 LSGI-AGAKDVRVSQMIHNTVLGMAETGTEAEATTRVEYNFRPAKLNDTFVNFV--RKFLYMVLE 402

  Fly   392 AQNTL 396
            ..:.|
  Rat   403 PNSEL 407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42De	NP_610246.3	SERPIN	31..401	CDD:238101	105/381 (28%)
LOC299277	XP_008763124.2	serpinA3_A1AC	37..417	CDD:381019	109/395 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010