DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42De and Serpina6

DIOPT Version :9

Sequence 1:	NP_610246.3	Gene:	Spn42De / 35602	FlyBaseID:	FBgn0033115	Length:	404	Species:	Drosophila melanogaster
Sequence 2:	NP_001009663.1	Gene:	Serpina6 / 299270	RGDID:	1595901	Length:	396	Species:	Rattus norvegicus

Alignment Length:	396	Identity:	105/396 - (26%)
Similarity:	175/396 - (44%)	Gaps:	32/396 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 TCSL-LLLQGLNLAMANTLNYSKSPAGEA----QFASQLFGQLAKSQSGRNIVFSPSSIRTGLAL 65
            ||.| |...||..|.|:|...|.|..|.|    .||..|:.:|......:|.:.||.||...||:
  Rat     7 TCLLWLCTSGLWTAQASTNESSNSHRGLAPTNVDFAFNLYQRLVALNPDKNTLISPVSISMALAM 71

  Fly    66 AYLGAEGSTADELKLGLGLEGAGKTEVAEKLDQL--LAKGQWEKASGDEDVPKLKYANRIFVTQR 128
            ..||: ..|.....||..|....:.|:.:....|  |.|   :..:|.|    :...|.:|:.|:
  Rat    72 VSLGS-AQTQSLQSLGFNLTETSEAEIHQSFQYLNYLLK---QSDTGLE----MNMGNAMFLLQK 128

  Fly   129 FKLTQTYQDLVSKNFAAAAENVNFTQKADTAKHINSWVEEQTHQQIKDLIAPESLDADTSAILVN 193
            .||..::...|.:.:.:.|..::|......::.||..|:::|..:|:.:.:  .||:..|.||||
  Rat   129 LKLKDSFLADVKQYYESEALAIDFEDWTKASQQINQHVKDKTQGKIEHVFS--DLDSPASFILVN 191

  Fly   194 AIYFKADWQSSFPDYATYASDFVNHGGRKVSVDTMSQE---DYFRFGELTELKAKVVELPYTGTD 255
            .|:.:..|:..|....|...||..:....|.|..|.|.   .|||.   :....:::::.|.|..
  Rat   192 YIFLRGIWELPFSPENTREEDFYVNETSTVKVPMMVQSGSIGYFRD---SVFPCQLIQMDYVGNG 253

  Fly   256 IVFLIILPQEEQGLAIVEEKLMGIDLNEISSQLRRRKVRVQLPKFKFEFDVPLQAALEELGIKKL 320
            ..| .|||.:.| :..|...|....::.....:..|:|.:.:|||.......|:..||:|.||.|
  Rat   254 TAF-FILPDQGQ-MDTVIAALSRDTIDRWGKLMTPRQVNLYIPKFSISDTYDLKDMLEDLNIKDL 316

  Fly   321 FSPGANLSSLYQGSEPLRISEVKHKAIIEVNEKGTTASGATFIKVSVESLTIGEEVFEFIADHPF 385
            .:..::.|...: ..||.::.| |||:::::| |.....:|    :...|.:..|..:...:.||
  Rat   317 LTNQSDFSGNTK-DVPLTLTMV-HKAMLQLDE-GNVLPNST----NGAPLHLRSEPLDIKFNKPF 374

  Fly   386 FFAIKD 391
            ...:.|
  Rat   375 ILLLFD 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42De	NP_610246.3	SERPIN	31..401	CDD:238101	94/370 (25%)
Serpina6	NP_001009663.1	alpha-1-antitrypsin_like	37..392	CDD:239011	92/366 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.110