Protein Alignment Spn42De and Serpinb1b

DIOPT Version :9

• Sequence 1: NP_610246.3
• Gene: Spn42De / 35602
• FlyBaseID: FBgn0033115
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: NP_766640.1
• Gene: Serpinb1b / 282663
• MGIID: 2445361
• Length: 382
• Species: Mus musculus
• Alignment Length: 398
• Identity: 143/398 - (35%)
• Similarity: 210/398 - (52%)
• Gaps: 35/398 - (8%)

  Fly    17 LAMANTLNYSKSPAGEAQFASQLFGQLAKSQSGRNIVFSPSSIRTGLALAYLGAEGSTADELKLG 81
            |:.||||           |..:||..|.:|....||.|||.||.:.||:.:|||:||||.:|...
Mouse     4 LSSANTL-----------FTLELFHTLKESSPTGNIFFSPFSISSSLAMVFLGAKGSTAAQLSKT 57

  Fly    82 LGLEGAGKTEVAEKLDQLLAKGQWEKASGDEDVPKLKYANRIFVTQRFKLTQTYQDLVSKNFAAA 146
            |..:..  .::......|.|:.....||     ..||.|||::..:.:.....:.....|.::|.
Mouse    58 LHFDSV--EDIHSCFQSLTAEVSKLGAS-----HTLKLANRLYGEKTYNFLPEFLASTQKMYSAD 115

  Fly   147 AENVNFTQKA-DTAKHINSWVEEQTHQQIKDLIAPESLDADTSAILVNAIYFKADWQSSFPDYAT 210
            ...|:|...: |..|.||.||:.||..:|.:|:|...:|:.|..:||||||||..|:..|....|
Mouse   116 LAAVDFQHASEDARKEINQWVKGQTEGKIPELLAKGVVDSMTKLVLVNAIYFKGIWEEQFMTRET 180

  Fly   211 YASDF-VNHGGRKVSVDTMSQEDYFRFGELTELKAKVVELPYTGTDIVFLIILPQ----EEQGLA 270
            ..:.| :|....| :|..|.|:..|.||.:::||.||:|:||.|.::..:|:||:    |..||.
Mouse   181 INAPFRLNKKDTK-TVKMMYQKKKFPFGYISDLKCKVLEMPYQGGELSMVILLPEDIEDESTGLK 244

  Fly   271 IVEEKLMGIDLNEIS--SQLRRRKVRVQLPKFKFEFDVPLQAALEELGIKKLFSPG-ANLSSLYQ 332
            .:||:|....|:|.:  ..||...|.|:||:||.|....|.:.|..||::.|||.| |:||.: .
Mouse   245 KIEEQLTLGKLHEWTKHENLRNIDVHVKLPRFKMEESYILNSNLCCLGVQDLFSSGKADLSGM-S 308

  Fly   333 GSEPLRISEVKHKAIIEVNEKGTTASGAT--FIKVSVESLTIGEEVFEFIADHPFFFAIK--DAQ 393
            ||..|.:|::.||:.::|||:||.|:.||  .|:|..|.:...:||  |..||||.|.|:  ...
Mouse   309 GSRDLFVSKIVHKSFVDVNEQGTEAAAATGGIIQVLCEKMPTPQEV--FTVDHPFLFFIRHNPTA 371

  Fly   394 NTLFLGHV 401
            |.:|.|.|
Mouse   372 NMIFFGRV 379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn42De	NP_610246.3	SERPIN	31..401	CDD:238101	137/382 (36%)
Serpinb1b	NP_766640.1	serpinB1_LEI	1..382	CDD:381028	143/398 (36%)
		CARD-binding motif (CBM). /evidence=ECO:0000250|UniProtKB:P30740	352..382		13/30 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.830