Protein Alignment Spn42De and Serpina3b

DIOPT Version :10

• Sequence 1: NP_610246.3
• Gene: Spn42De / 35602
• FlyBaseID: FBgn0033115
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: NP_766612.1
• Gene: Serpina3b / 271047
• MGIID: 2182835
• Length: 420
• Species: Mus musculus
• Alignment Length: 398
• Identity: 121/398 - (30%)
• Similarity: 190/398 - (47%)
• Gaps: 37/398 - (9%)

  Fly    12 LQGLNLAMANTLNYSKSPAGEAQFASQLFGQLAKSQSGRNIVFSPSSIRTGLALAYLGAEGSTAD 76
            |..|.||..||           .||...:.:||.....:||.|||..|.|.|....|||:|:|.:
Mouse    42 LDSLTLASINT-----------DFAFSFYKELALKNPHKNIAFSPFGIATALNSLTLGAKGNTLE 95

  Fly    77 EL--KLGLGLEGAGKTEVAEKLDQLLAKGQWEKASGDEDVPKLKYANRIFVTQRFKLTQTYQDLV 139
            |:  .|...|....:.::.:....||     ::.|...|..:::..|.:||.:..::...:::..
Mouse    96 EILEVLKFNLTETSEADIHQGFKHLL-----QRLSHPGDQVQIRTGNALFVEKHLQILAEFKEKA 155

  Fly   140 SKNFAAAAENVNFTQKADTAKHINSWVEEQTHQQIKDLIAPESLDADTSAILVNAIYFKADWQSS 204
            ...:.......||.|..:..|.|||::..||..:||:|::  .:|.:||.::||.::|||:|...
Mouse   156 RALYHTEVFTANFQQPHEAMKLINSYMSNQTQGKIKELVS--DMDGNTSMVIVNDLFFKAEWMVP 218

  Fly   205 FPDYATYASDFVNHGGRKVSVDTMSQED----YFRFGELTELKAKVVELPYTGTDIVFLIILPQE 265
            |....|:...|:....|.|.|..|..::    |||.   .|||..||||.|.|.... :.|||
Mouse   219 FNSDDTFMGKFIVDRSRHVKVPMMKTKNLRTPYFRD---EELKCTVVELNYKGNGKA-MFILP-- 277

  Fly   266 EQG-LAIVEEKLMGIDLNEISSQLRRRKVR-VQLPKFKFEFDVPLQAALEELGIKKLFSPGANLS 328
            :|| :..||..|....|.:....||.||:: :.||||.......|:..|.||||::|||..|:||
Mouse   278 DQGKMQQVEASLQPGTLKKWRKSLRPRKIKELHLPKFSLSQHYNLEDILPELGIRELFSTQADLS 342

  Fly   329 SLYQGSEPLRISEVKHKAIIEVNEKGTTASGATFIKVSVESLTIGEEVFEFIADHPFFFAIKDAQ 393
            .: .|.:.:.:||:.|...:::.||||.....|.:..:..|..: :.||....|. |.:.:.| |
Mouse   343 GI-TGVKNITVSEMIHSTELDMTEKGTEGDAITIVGYNFMSAKL-KPVFVKFEDQ-FLYIVLD-Q 403

  Fly   394 NTLFLGHV 401
            ..|:: ||
Mouse   404 GDLWI-HV 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn42De	NP_610246.3	serpin42Dd-like_insects	30..403	CDD:381070	115/380 (30%)
Serpina3b	NP_766612.1	serpinA3_A1AC	37..418	CDD:381019	121/398 (30%)
		RCL	367..392		6/25 (24%)