Protein Alignment Spn42De and SERPINA11

DIOPT Version :9

• Sequence 1: NP_610246.3
• Gene: Spn42De / 35602
• FlyBaseID: FBgn0033115
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: NP_001073920.1
• Gene: SERPINA11 / 256394
• HGNCID: 19193
• Length: 422
• Species: Homo sapiens
• Alignment Length: 384
• Identity: 121/384 - (31%)
• Similarity: 183/384 - (47%)
• Gaps: 41/384 - (10%)

  Fly    35 FASQLFGQLAKSQSGRNIVFSPSSIRTGLALAYLGAEGSTADELKLGLGLEGAG--KTEVAE--- 94
            ||.:|:.:||....| ||.|||.||.|.|||..|||:.:|:     .|.|||.|  .||..|
Human    57 FALRLYKELAADAPG-NIFFSPVSISTTLALLSLGAQANTS-----ALILEGLGFNLTETPEADI 115

  Fly    95 -----KLDQLLAKGQWEKASGDEDVPK--LKYANRIFVTQRFKLTQTYQDLVSKNFAAAAENVNF 152
                 .|...||...          ||  ||..|.:|:.:|.|..|.|.|.:.:.:.|.|.:.||
Human   116 HQGFRSLLHTLALPS----------PKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANF 170

  Fly   153 TQKADTAKHINSWVEEQTHQQIKDLIAPESLDADTSAILVNAIYFKADWQSSFPDYATYASD--F 215
            |....|.:.||.::..||:.|:.|.: || ...||..:|.|.|:|||.|:..|..|.|...:  |
Human   171 TDSVTTGRQINDYLRRQTYGQVVDCL-PE-FSQDTFMVLANYIFFKAKWKHPFSRYQTQKQESFF 233

  Fly   216 VNHGGRKVSVDTMSQEDYFRFGELTELKAKVVELPYTGTDIVFLIILPQEEQGLAIVEEKLMGID 280
            |:. ...:.|..|.|::..||....:|...|:::.|.|..:. |::||...: :..||..|....
Human   234 VDE-RTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALA-LLVLPDPGK-MKQVEAALQPQT 295

  Fly   281 LNEISSQLRRRKVRVQLPKFKFEFDVPLQAALEELGIKKLFSPGANLSSLYQGSEPLRISEVKHK 345
            |.:....|....:.:.||:|.......|:..|.::|:..:.:..|:.|.: .|.....||:|.||
Human   296 LRKWGQLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFSGV-TGQLNKTISKVSHK 359

  Fly   346 AIIEVNEKGTTASGATFIKVSVESL-TIGEEVFEFIADHPFFFAIKD--AQNTLFLGHV 401
            |:::::||||.|..|:.:.....|| |:.:....|  :.||...:.:  .|:.||||.|
Human   360 AMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHF--NRPFLLLLWEVTTQSLLFLGKV 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn42De	NP_610246.3	SERPIN	31..401	CDD:238101	120/382 (31%)
SERPINA11	NP_001073920.1	alpha-1-antitrypsin_like	53..416	CDD:239011	120/382 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.010