DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42De and Serpina3c

DIOPT Version :9

Sequence 1:	NP_610246.3	Gene:	Spn42De / 35602	FlyBaseID:	FBgn0033115	Length:	404	Species:	Drosophila melanogaster
Sequence 2:	NP_036789.2	Gene:	Serpina3c / 24794	RGDID:	2972	Length:	416	Species:	Rattus norvegicus

Alignment Length:	401	Identity:	130/401 - (32%)
Similarity:	197/401 - (49%)	Gaps:	37/401 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LQGLNLAMANTLNYSKSPAGEAQFASQLFGQLAKSQSGRNIVFSPSSIRTGLALAYLGAEGSTAD 76
            |..|.||..||           .|...|:.:||.....:|:||||.||...||:..|||:.||.:
  Rat    40 LHSLTLASINT-----------DFTLSLYKKLALRNPDKNVVFSPLSISAALAILSLGAKDSTME 93

  Fly    77 ELKLGL--GLEGAGKTEVAEKLDQLLAKGQWEKASGDEDVPKLKYANRIFVTQRFKLTQTYQDLV 139
            |:..||  .|....:.|:.:....||     ::.|..||..::...:.:|:.:...:...:|:..
  Rat    94 EILEGLKFNLTEITEEEIHQGFGHLL-----QRLSQPEDQAEINTGSALFIDKEQPILSEFQEKT 153

  Fly   140 SKNFAAAAENVNFTQKADTAKHINSWVEEQTHQQIKDLIAPESLDADTSAILVNAIYFKADWQSS 204
            ...:.|.|...:|.|..:..|.||.:|..||..:|.:|.:  .||..||.:|||.:.||..|:..
  Rat   154 RALYQAEAFVADFKQCNEAKKFINDYVSNQTQGKIAELFS--DLDERTSMVLVNYLLFKGKWKVP 216

  Fly   205 FPDYATYASDFVNHGGRKVSVDTMSQED----YFRFGELTELKAKVVELPYTGTDIVFLIILPQE 265
            |....|:.|:|.....|.|.|..|..:|    |.|.   .||...|:||.||| :...|.|||
  Rat   217 FNPNDTFESEFYLDEKRSVKVPMMKIKDLTTPYVRD---EELSCSVLELKYTG-NASALFILP-- 275

  Fly   266 EQG-LAIVEEKLMGIDLNEISSQLRRRKV-RVQLPKFKFEFDVPLQAALEELGIKKLFSPGANLS 328
            :|| :..||..|....|.:....||.|.: .:::|||....|..|:..|.||||:|:||..|:||
  Rat   276 DQGKMQQVESSLQPETLKKWKDSLRPRIISELRMPKFSISTDYNLEEVLPELGIRKIFSQQADLS 340

  Fly   329 SLYQGSEPLRISEVKHKAIIEVNEKGTTASGATFIKVSVESLTIGEEVFEFIADHPFFFAIKD-- 391
            .: .|::.|.:|:|.|||:::|:|.||..:.||.:..:::||.....:..|  :.||...|.|
  Rat   341 RI-TGTKNLHVSQVVHKAVLDVDETGTEGAAATAVTAALKSLPQTVPLLNF--NRPFMLVITDNN 402

  Fly   392 AQNTLFLGHVS 402
            .|:..|:|.|:
  Rat   403 GQSVFFMGKVT 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42De	NP_610246.3	SERPIN	31..401	CDD:238101	123/379 (32%)
Serpina3c	NP_036789.2	SERPIN	54..415	CDD:214513	123/376 (33%)
Serpina3c	NP_036789.2	RCL	365..392		7/28 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010