DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42De and Serpina3j

DIOPT Version :9

Sequence 1:	NP_610246.3	Gene:	Spn42De / 35602	FlyBaseID:	FBgn0033115	Length:	404	Species:	Drosophila melanogaster
Sequence 2:	NP_001094942.1	Gene:	Serpina3j / 238395	MGIID:	2182843	Length:	420	Species:	Mus musculus

Alignment Length:	401	Identity:	116/401 - (28%)
Similarity:	181/401 - (45%)	Gaps:	37/401 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LQGLNLAMANTLNYSKSPAGEAQFASQLFGQLAKSQSGRNIVFSPSSIRTGLALAYLGAEGSTAD 76
            |..|.||..||           .||..|:.:||.....:|.||||.||...||...|||:|:|.:
Mouse    42 LDSLTLASINT-----------DFAFSLYKKLALKNPHKNFVFSPLSITIALASLSLGAKGNTLE 95

  Fly    77 ELKLGL--GLEGAGKTEVAEKLDQLLAKGQWEKASGDEDVPKLKYANRIFVTQRFKLTQTYQDLV 139
            |:..||  .|....:.::.:....||     ::.|...|..::...|.:.|.:..::...:::..
Mouse    96 EILEGLKFNLTETPEADIHQGFGHLL-----QRLSQPGDQVQISTGNSMVVEKHLQILAEFKEKA 155

  Fly   140 SKNFAAAAENVNFTQKADTAKHINSWVEEQTHQQIKDLIAPESLDADTSAILVNAIYFKADWQSS 204
            ...:.......:|.|..:..|.:|.:|..||...||:|::  .|:..||.::.|...|...|..:
Mouse   156 RALYHTEVFTADFQQPREARKLLNDYVSNQTQGMIKELVS--DLEERTSMVMTNFALFNGKWNMT 218

  Fly   205 FPDYATYASDFVNHGGRKVSVDTMSQED----YFRFGELTELKAKVVELPYTGTDIVFLIILPQE 265
            |..|.|:...|:......|.|..|..::    |||.   .::|..||||.|.|.... :.|||
Mouse   219 FDPYETFMGTFIEDRRTPVKVSMMKMKELRAPYFRD---EKMKCTVVELNYKGNGKA-MFILP-- 277

  Fly   266 EQG-LAIVEEKLMGIDLNEISSQLRRRKV-RVQLPKFKFEFDVPLQAALEELGIKKLFSPGANLS 328
            :|| :..||..|....|......||.|.: .:.||||....:..|:..|.|||||::||..|:||
Mouse   278 DQGKMKQVEASLQPATLRGWRKSLRPRMIDELYLPKFSISKNYRLENILPELGIKEVFSTQADLS 342

  Fly   329 SLYQGSEPLRISEVKHKAIIEVNEKGTTASGATFIKVSVESLTIGEEVFEFIADHPFFFAI--KD 391
            .: .|.:.:|:|.:.|.|.:::.|.||.|...|..|....|......|...  :.||.|.:  .|
Mouse   343 GI-SGGKDVRVSRMFHSAALDMTETGTEARATTRDKYDFLSTKSNPTVVNL--NTPFLFCVLHSD 404

  Fly   392 AQNTLFLGHVS 402
            ::|..|:|.::
Mouse   405 SENIDFMGKIN 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42De	NP_610246.3	SERPIN	31..401	CDD:238101	110/379 (29%)
Serpina3j	NP_001094942.1	serpinA3_A1AC	37..417	CDD:381019	116/401 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010