DRSC/TRiP Functional Genomics Resources

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Protein Alignment Spn42De and Serpina3n

DIOPT Version :9

Sequence 1:NP_610246.3 Gene:Spn42De / 35602 FlyBaseID:FBgn0033115 Length:404 Species:Drosophila melanogaster
Sequence 2:NP_033278.2 Gene:Serpina3n / 20716 MGIID:105045 Length:418 Species:Mus musculus


Alignment Length:406 Identity:133/406 - (32%)
Similarity:205/406 - (50%) Gaps:47/406 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly    12 LQGLNLAMANTLNYSKSPAGEAQFASQLFGQLAKSQSGRNIVFSPSSIRTGLALAYLGAEGSTAD 76
            |..|.||..||           .||..|:.:|......:||||||.||...||:..|||:|:|.:
Mouse    42 LDSLTLASINT-----------DFAFSLYKELVLKNPDKNIVFSPLSISAALAVMSLGAKGNTLE 95

  Fly    77 ELKLGL--GLEGAGKTEVAEKLDQLLAKGQWEKASGDEDVPKLKYANRIFVTQRFKLTQTYQDLV 139
            |:..||  .|....:.::.:....||     ::.:..:|..::...:.:|:.:|.::...:|:..
Mouse    96 EILEGLKFNLTETSEADIHQGFGHLL-----QRLNQPKDQVQISTGSALFIEKRQQILTEFQEKA 155

  Fly   140 SKNFAAAAENVNFTQKADTAKHINSWVEEQTHQQIKDLIAPESLDADTSAILVNAIYFKADWQSS 204
            ...:.|.|...:|.|.....|.||.:|.:||...||:|::  .||..|..:|||.|||||.|:..
Mouse   156 RALYQAEAFTADFQQPRQAKKLINDYVRKQTQGMIKELVS--DLDKRTLMVLVNYIYFKAKWKVP 218

  Fly   205 FPDYATYASDFVNHGGRKVSVDTMSQED----YFRFGELTELKAKVVELPYTGTDIVFLIILPQE 265
            |....|:.|:|.....|.|.|..||.||    |||.   .||...||||.||| :...:.|||  
Mouse   219 FDPLDTFKSEFYAGKRRPVIVPMMSMEDLTTPYFRD---EELFCTVVELKYTG-NASAMFILP-- 277

  Fly   266 EQG-LAIVEEKLMGIDLNEISSQLRRRKV-RVQLPKFKFEFDVPLQAALEELGIKKLFSPGANLS 328
            :|| :..||..|....|.:..:.|:.|.: .:.||||....|..|:..|.:|||:::||..|:||
Mouse   278 DQGKMQQVEASLQPETLRKWKNSLKPRMIDELHLPKFSISTDYSLEDVLSKLGIREVFSTQADLS 342

  Fly   329 SLYQGSEPLRISEVKHKAIIEVNEKGTTASGAT---FIKVSVE--SLTIGEEVFEFIADHPFFFA 388
            :: .|::.||:|:|.|||:::|.|.||.|:.||   |:.:|.:  .||:       ..:.||...
Mouse   343 AI-TGTKDLRVSQVVHKAVLDVAETGTEAAAATGVKFVPMSAKLYPLTV-------YFNRPFLIM 399

  Fly   389 IKDAQNTL--FLGHVS 402
            |.|.:..:  |:..::
Mouse   400 IFDTETEIAPFIAKIA 415

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Spn42DeNP_610246.3 SERPIN 31..401 CDD:238101 127/384 (33%)
Serpina3nNP_033278.2 serpinA3_A1AC 37..418 CDD:381019 133/406 (33%)
RCL 367..392 9/31 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR11461
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X28
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
33.010

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