DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42De and Serpina3k

DIOPT Version :9

Sequence 1:	NP_610246.3	Gene:	Spn42De / 35602	FlyBaseID:	FBgn0033115	Length:	404	Species:	Drosophila melanogaster
Sequence 2:	NP_035588.2	Gene:	Serpina3k / 20714	MGIID:	98377	Length:	418	Species:	Mus musculus

Alignment Length:	403	Identity:	129/403 - (32%)
Similarity:	191/403 - (47%)	Gaps:	48/403 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 LNLAMANTLNYSKSPAGEAQFASQLFGQLAKSQSGRNIVFSPSSIRTGLALAYLGAEGSTADELK 79
            |.||..||           .||..|:.:||.....:||||||.||...|||..|||:|.|.:|:.
Mouse    46 LTLASVNT-----------DFAFSLYKKLALKNQDKNIVFSPLSISAALALVSLGAKGKTMEEIL 99

  Fly    80 LGL--GLEGAGKTEVAEKLDQLLAKGQWEKASGDEDVPKLKYANRIFVTQRFKLTQTYQDLVSKN 142
            .||  .|....:.::.:....||     :..|..||..::...|.:|:.:..::...:.:.....
Mouse   100 EGLKFNLTETPEADIHQGFGNLL-----QSLSQPEDQDQINIGNAMFIEKDLQILAEFHEKTRAL 159

  Fly   143 FAAAAENVNFTQKADTAKHINSWVEEQTHQQIKDLIAPESLDADTSAILVNAIYFKADWQSSFPD 207
            :...|...:|.|..:....||.:|..||...||.||:  .||..|..:|||.||||..|:.||..
Mouse   160 YQTEAFTADFQQPTEAKNLINDYVSNQTQGMIKKLIS--ELDDGTLMVLVNYIYFKGKWKISFDP 222

  Fly   208 YATYASDFVNHGGRKVSVDTMSQE----DYFRFGELTELKAKVVELPYTGTDIVFLIILPQEEQG 268
            ..|:.|:|.....|.|.|..|..:    .:||.   .||...|:||.||| :...|:|||  :||
Mouse   223 QDTFESEFYLDEKRSVKVPMMKMKLLTARHFRD---EELSCSVLELKYTG-NASALLILP--DQG 281

  Fly   269 -LAIVEEKLMGIDLNE-----ISSQLRRRKVRVQLPKFKFEFDVPLQA-ALEELGIKKLFSPGAN 326
             :..||..|....|.:     .|||:.    .:.||||....|..|:. .|.|:|||::|:..|:
Mouse   282 RMQQVEASLQPETLRKWRKTLFSSQIE----ELNLPKFSIASDYRLEEDVLPEMGIKEVFTEQAD 342

  Fly   327 LSSLYQGSEPLRISEVKHKAIIEVNEKGTTASGATFIKVSVESLTIGEEVFEFIADHPFFFAI-- 389
            ||.:.: ::.|.:|:|.|||:::|.|.||.|:.||.:...:....:....|    :.||...|
Mouse   343 LSGITE-AKKLSVSQVVHKAVLDVAETGTEAAAATGVIGGIRKAVLPAVCF----NRPFLIVIYH 402

  Fly   390 KDAQNTLFLGHVS 402
            ..||:.||:..|:
Mouse   403 TSAQSILFMAKVN 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42De	NP_610246.3	SERPIN	31..401	CDD:238101	123/384 (32%)
Serpina3k	NP_035588.2	SERPIN	57..417	CDD:214513	122/381 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.010