Protein Alignment Spn42De and Serpini1

DIOPT Version :9

• Sequence 1: NP_610246.3
• Gene: Spn42De / 35602
• FlyBaseID: FBgn0033115
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: NP_033276.1
• Gene: Serpini1 / 20713
• MGIID: 1194506
• Length: 410
• Species: Mus musculus
• Alignment Length: 386
• Identity: 117/386 - (30%)
• Similarity: 206/386 - (53%)
• Gaps: 37/386 - (9%)

  Fly    34 QFASQLFGQLAKSQSGRNIVFSPSSIRTGLALAYLGAEGSTADELKLGLGLEGAGKTEVAEKLDQ 98
            :::..::..|..:....||:|||.||...:.:..|||:|||..|::..:|.||
Mouse    28 EWSVNMYNHLRGTGEDENILFSPLSIALAMGMMELGAQGSTRKEIRHSMGYEG------------ 80

  Fly    99 LLAKGQWE---------KASGDEDVPKLKYANRIFVTQRFKLTQTYQDLVSKNFAAAAENVNFTQ 154
              .||..|         .||.:|:...:|.||.:||...|.:.:.:..::...|.|...:|:|:|
Mouse    81 --LKGGEEFSFLRDFSNMASAEENQYVMKLANSLFVQNGFHVNEEFLQMLKMYFNAEVNHVDFSQ 143

  Fly   155 KADTAKHINSWVEEQTHQQIKDLIAPESLDADTSAILVNAIYFKADWQSSFPDYATYASDFVNHG 219
            ....|..||.|||..|:..:|||::||..|..|:..|:||:|||.:|:|.|....|....|....
Mouse   144 NVAVANSINKWVENYTNSLLKDLVSPEDFDGVTNLALINAVYFKGNWKSQFRPENTRTFSFTKDD 208

  Fly   220 GRKVSVDTMSQEDYFRFGELTELK------AKVVELPYTGTDIVFLIILPQEEQGLAIVEEKLMG 278
            ..:|.:..|.|:..|.:||.::..      .:|:|:||.|.:|..::.|.::|..||.:|..|..
Mouse   209 ESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLALSRQEVPLATLEPLLKA 273

  Fly   279 IDLNEISSQLRRRKVRVQLPKFKFEFDVPLQAALEELGIKKLFSPGANLSSLYQGSEPLRISEVK 343
            ..:.|.::.::::||.|.||:|..|.::.|:..|:.||:.::|...|||:::....| |.:|:..
Mouse   274 QLIEEWANSVKKQKVEVYLPRFTVEQEIDLKDILKALGVTEIFIKDANLTAMSDKKE-LFLSKAV 337

  Fly   344 HKAIIEVNEKGTTASGATFIKVSVESLTIGEEVF-EFIADHPFFFAIKDAQN--TLFLGHV 401
            ||:.|||||:|:.|:.|:.: :::..:.:   :: :.|.||||.:.|::.::  .||:|.|
Mouse   338 HKSCIEVNEEGSEAAAASGM-IAISRMAV---LYPQVIVDHPFLYLIRNRKSGIILFMGRV 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn42De	NP_610246.3	SERPIN	31..401	CDD:238101	116/384 (30%)
Serpini1	NP_033276.1	neuroserpin	23..410	CDD:239003	117/386 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	230	1.000	Domainoid score	I2434
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	233	1.000	Inparanoid score	I3407
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3483
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.910