DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42De and Serpina16

DIOPT Version :9

Sequence 1:	NP_610246.3	Gene:	Spn42De / 35602	FlyBaseID:	FBgn0033115	Length:	404	Species:	Drosophila melanogaster
Sequence 2:	XP_112098.3	Gene:	Serpina16 / 194604	MGIID:	2684892	Length:	440	Species:	Mus musculus

Alignment Length:	392	Identity:	96/392 - (24%)
Similarity:	170/392 - (43%)	Gaps:	28/392 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 TLNYSKSPA--------GEAQFASQLFGQLAKSQSGRNIVFSPSSIRTGLA-LAYLGAEGSTADE 77
            |.|.|::||        ...:||..|:.||.||:.|:|::|||.||...|. ||:.....:....
Mouse    51 TSNTSRTPAIQGAPPFFNNQKFALSLYTQLPKSKLGKNVIFSPLSITMPLVLLAFQDKPEARRQV 115

  Fly    78 LK-LGLGLEGAGKTEVAEKLDQLLAKGQWEKASGDEDVPKLKYANRIFVTQRFKLTQTYQDLVSK 141
            |: ||.|:.||...:.|.:..:||:.....:..|      :...:..|:.:..|...|:..|.:.
Mouse   116 LQGLGFGVTGALDAKAAVQYGKLLSALLPAEHCG------IHTGSLFFIDKTLKPQTTFLTLANS 174

  Fly   142 NFAAAAENVNFTQKADTAKHINSWVEEQTHQQIKDLIAPESLDADTSAILVNAIYFKADWQSSFP 206
            ::::....::|.......|.|:..::.:|..::..|:  .:|...|...|.|...||..|:..|.
Mouse   175 SYSSDVILISFGNHKLAKKQIDLAIKVKTQGKVTRLL--RNLKPPTHLFLTNYNLFKGKWKYRFN 237

  Fly   207 DYATYASDFVNHGGRKVSVDTMSQEDYFRFGELTELKAKVVELPYTGTDIVFLIILPQEEQGLAI 271
            ...|...:|....|..:.|..|.:..:|:....:.:.:.|::||:| .:|..:..||.:.. |..
Mouse   238 PKYTGMRNFSLSNGTNILVPMMQKIGWFQLKYFSHIHSYVLQLPFT-CNISGVFFLPNDGD-LKE 300

  Fly   272 VEEKLMGIDLNEISSQLRRRKVRVQLPKFKFEFDVPLQAALEELGIKKLFSPGANLSSLYQGSEP 336
            .|:.|:....|........||..:..|||.....:.|::........|||:...:||.:.....|
Mouse   301 CEKALLEQSFNTWIQPFPLRKRWLFFPKFSIPVALQLESFKHVNSSLKLFNKRMDLSGITLQKAP 365

  Fly   337 LRISEVKHKAIIEVNEKGTTASGATFIKVSVESLTIGEEVFEFIADHPFFFAIKD--AQNTLFLG 399
            ||::...|:|.:.|:|.| .....:..:|:.|.   |.....|  :..|...|.|  :::.||:|
Mouse   366 LRVTMAVHRAELAVSEDG-EGEDVSNSRVNPEP---GLAALHF--NRSFLLLILDEASKSLLFMG 424

  Fly   400 HV 401
            .|
Mouse   425 RV 426

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42De	NP_610246.3	SERPIN	31..401	CDD:238101	90/373 (24%)
Serpina16	XP_112098.3	serpin	61..431	CDD:393296	91/382 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.100