DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Spn42De and Serpina3c

DIOPT Version :9

Sequence 1:	NP_610246.3	Gene:	Spn42De / 35602	FlyBaseID:	FBgn0033115	Length:	404	Species:	Drosophila melanogaster
Sequence 2:	XP_011242304.1	Gene:	Serpina3c / 16625	MGIID:	102848	Length:	436	Species:	Mus musculus

Alignment Length:	402	Identity:	133/402 - (33%)
Similarity:	194/402 - (48%)	Gaps:	42/402 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LQGLNLAMANTLNYSKSPAGEAQFASQLFGQLAKSQSGRNIVFSPSSIRTGLALAYLGAEGSTAD 76
            |..|.||..||           .||..|:.:||......||||||.||...||:..|||:|:|.:
Mouse    61 LDSLTLASINT-----------DFAFSLYKKLALKNPDTNIVFSPLSISAALAIVSLGAKGNTLE 114

  Fly    77 ELKLGL--GLEGAGKTEVAEKLDQLLAKGQWEKASGDEDVPKLKYANRIFVTQRFKLTQTYQDLV 139
            |:..||  .|....:.::.:....||     ::.|...:..::...:.:||.:..::...:|:..
Mouse   115 EILEGLNFNLTETPEADIHQGFGHLL-----QRLSHPGEQVQISTGSALFVEKHLQILAEFQEKA 174

  Fly   140 SKNFAAAAENVNFTQKADTAKHINSWVEEQTHQQIKDLIAPESLDADTSAILVNAIYFKADWQSS 204
            ...:.|.|...:|.|..:..|.||.:|..||.::||.||:  .||.||..:|||.||||..|:..
Mouse   175 RALYQAEAFTADFQQPLEATKLINDYVSNQTQRKIKGLIS--DLDTDTLMVLVNYIYFKGKWKMP 237

  Fly   205 FPDYATYASDFVNHGGRKVSVDTMS----QEDYFRFGELTELKAKVVELPYTGTDIVFLIILPQE 265
            |....|:.|:|.....|.|.|..|.    ...|||.   .||...||||.|.| :...|.|||
Mouse   238 FNPRDTFESEFYLDVKRSVKVPMMKIKTLTTPYFRD---EELSCTVVELKYKG-NASALFILP-- 296

  Fly   266 EQG-LAIVEEKLMGIDLNEISSQLRRRKV-RVQLPKFKFEFDVPLQAALEELGIKKLFSPGANLS 328
            :|| :..||..|....|.:..:.||.||: .:.||||....|..|:..|.|||||::||..|:||
Mouse   297 DQGRMQQVEASLQPETLRKWKNSLRPRKMGELYLPKFSISTDYSLKNILPELGIKEIFSKQADLS 361

  Fly   329 SLYQGSEPLRISEVKHKAIIEVNEKGT---TASGATFIKVSVESLTIGEEVFEFIADHPFFFAIK 390
            .: .|::.|.:|::.|||:::|.|.||   .|:|..|..:|..:.......|..:..|      .
Mouse   362 GI-TGTKDLIVSQMVHKAVLDVAETGTEGVAATGVNFRILSRRTSLWFNRTFLMVISH------T 419

  Fly   391 DAQNTLFLGHVS 402
            |.|.|||:..::
Mouse   420 DVQTTLFIAKIT 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42De	NP_610246.3	SERPIN	31..401	CDD:238101	127/380 (33%)
Serpina3c	XP_011242304.1	serpinA3_A1AC	56..434	CDD:381019	133/402 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010