DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42De and Serpina6

DIOPT Version :9

Sequence 1:	NP_610246.3	Gene:	Spn42De / 35602	FlyBaseID:	FBgn0033115	Length:	404	Species:	Drosophila melanogaster
Sequence 2:	NP_031644.1	Gene:	Serpina6 / 12401	MGIID:	88278	Length:	397	Species:	Mus musculus

Alignment Length:	421	Identity:	108/421 - (25%)
Similarity:	176/421 - (41%)	Gaps:	81/421 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 TCSL-LLLQGLNLAMANTLNYSKSPAGEA----QFASQLFGQLAKSQSGRNIVFSPSSIRTGLAL 65
            ||.. |...||....|.|...|.|....|    .||..|:.:|....|.:|.:.||.||...||:
Mouse     7 TCLFWLCTSGLWTTQAVTDEDSSSHRDLAPTNVDFAFNLYKRLVALNSDKNTLISPVSISMALAM 71

  Fly    66 AYLGAEGSTADELKLGLGLEGAGKTEV---AEKLDQLLAKGQWEKASGDEDVPKLKYANRIFVTQ 127
            ..|...|||.....||..:....:.|:   .:.|:.||.:..    :|.|    :...|.:|:.|
Mouse    72 LSLSTRGSTQYLENLGFNMSKMSEAEIHQGFQYLNSLLQQSD----TGLE----MNMGNVMFLLQ 128

  Fly   128 RFKL-------TQTYQD-----LVSKNFAAAAENVNFTQKADTAKHINSWVEEQTHQQIKDLIAP 180
            ..||       |:.|.:     :.||::..|.|            .||:.|:.:|..:|:.:::
Mouse   129 NLKLKDSFLADTKHYYESEALTIPSKDWTKAGE------------QINNHVKNKTQGKIEHVVS- 180

  Fly   181 ESLDADTSAILVNAIYFKADWQSSFPDYATYASDFVNHGGRKVSVDTMSQE---DYFRFGELTEL 242
             .||:..:.||:|.|:.|..|:..|....|...||..:....|.|..|.|.   .|||.   :.:
Mouse   181 -DLDSSATLILINYIFLKGIWKLPFSPENTREEDFYVNETSTVKVPMMVQSGNISYFRD---SAI 241

  Fly   243 KAKVVELPYTGTDIVFLIILPQEEQGLAIVEEKLMGIDLNEISSQLRR------------RKVRV 295
            ..::|::.|.|....| ||||.:.|             ::.:.:.|.|            |::.:
Mouse   242 PCQMVQMNYVGNGTTF-IILPDQGQ-------------MDTVVAALNRDTIDRWGKLMIPRQMNL 292

  Fly   296 QLPKFKFEFDVPLQAALEELGIKKLFSPGANLSSLYQGSEPLRISEVKHKAIIEVNEKGTTASGA 360
            .:|||.......||..|.::|||.||:..::.:...:.: ||.:: |.|||:::::| |.....|
Mouse   293 YIPKFSMSDTYDLQDVLADVGIKDLFTNQSDFADTTKDT-PLTLT-VLHKAMLQLDE-GNVLPAA 354

  Fly   361 TFIKVSVESLTIGEEVFEFIADHPFFFAIKD 391
            |    :...:.:..|.|....:.||.|...|
Mouse   355 T----NGPPVHLPSESFTLKYNRPFIFLAFD 381

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42De	NP_610246.3	SERPIN	31..401	CDD:238101	99/395 (25%)
Serpina6	NP_031644.1	SERPIN	43..396	CDD:214513	96/385 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020