DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Spn42De and Serping1

DIOPT Version :9

Sequence 1:	NP_610246.3	Gene:	Spn42De / 35602	FlyBaseID:	FBgn0033115	Length:	404	Species:	Drosophila melanogaster
Sequence 2:	NP_033906.2	Gene:	Serping1 / 12258	MGIID:	894696	Length:	504	Species:	Mus musculus

Alignment Length:	401	Identity:	100/401 - (24%)
Similarity:	175/401 - (43%)	Gaps:	69/401 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 SKSPAGEA--QFASQLFGQLAKSQSGR-NIVFSPSSIRTGLALAYLGAEGSTADELKLGL----- 82
            |::...||  .|:.:|:...:.::..: |:.|||.||.:.|....|||..||...|:..|
Mouse   143 SEAKLSEALTDFSVKLYHAFSATKMAKTNMAFSPFSIASLLTQVLLGAGDSTKSNLESILSYPKD 207

  Fly    83 ---------GLEGAGKTEVAEKLDQLLAKGQWEKASGDEDVPKLKYANRIFVTQRFKLTQTYQDL 138
                     |....|.|.|::                            ||.:....:..||.:
Mouse   208 FACVHQALKGFSSKGVTSVSQ----------------------------IFHSPDLAIRDTYVN- 243

  Fly   139 VSKNFAAAAENVNFTQKADTAKHINSWVEEQTHQQIKDLIAPESLDADTSAILVNAIYFKADWQS 203
            .|::...::..|.....|...:.||:||.|.|:.:|:.|:  :||.:||..:|:||:|..|.|:.
Mouse   244 ASQSLYGSSPRVLGPDSAANLELINTWVAENTNHKIRKLL--DSLPSDTCLVLLNAVYLSAKWKI 306

  Fly   204 SFPDYATYASDFVNHGGRKVSVDTMSQEDY--FRFGELTELKAKVVELPYTGTDIVFLIILPQ-E 265
            :|......|..|..:.  .:.|..||...|  .:|.:.| |||||.:|..: .::.|:|::|. .
Mouse   307 TFEPKKMMAPFFYKNS--MIKVPMMSSVKYPVAQFDDHT-LKAKVGQLQLS-HNLSFVIVVPVFP 367

  Fly   266 EQGLAIVEEKLMGIDLNEISSQLRRRK---VRVQLPKFKFEFDVPLQAALEELGIKKLFSPGANL 327
            :..|..||:.|.......|..:|...|   ..:.:|..|.:....:.:.:|:|.... |:...||
Mouse   368 KHQLKDVEKALNPTVFKAIMKKLELSKFLPTYLTMPHIKVKSSQDMLSVMEKLEFFD-FTYDLNL 431

  Fly   328 SSLYQGSEPLRISEVKHKAIIEVNEKGTTASGATFIKVSVESLTIGEEVFEFIADHPFFFAIKDA 392
            ..|.:..: |::|.:||:.::|:.|.|..|:.|:       :::.|..:..|....||.|.:.|.
Mouse   432 CGLTEDPD-LQVSAMKHETVLELTESGVEAAAAS-------AISFGRSLPIFEVQRPFLFLLWDQ 488

  Fly   393 QN--TLFLGHV 401
            |:  .:|:|.|
Mouse   489 QHRFPVFMGRV 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42De	NP_610246.3	SERPIN	31..401	CDD:238101	98/394 (25%)
Serping1	NP_033906.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	22..67
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	85..141
		serpinG1_C1-INH	141..500	CDD:381006	100/401 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010