DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42De and LOC100909605

DIOPT Version :9

Sequence 1:	NP_610246.3	Gene:	Spn42De / 35602	FlyBaseID:	FBgn0033115	Length:	404	Species:	Drosophila melanogaster
Sequence 2:	XP_006240581.2	Gene:	LOC100909605 / 100909605	RGDID:	6502633	Length:	410	Species:	Rattus norvegicus

Alignment Length:	382	Identity:	128/382 - (33%)
Similarity:	194/382 - (50%)	Gaps:	34/382 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 FASQLFGQLAKSQSGRNIVFSPSSIRTGLALAYLGAEGSTADELKLGL--GLEGAGKTEVAEKLD 97
            ||..|:.:|......:|||||..||.|.|.|..|||:.:|..|:..||  .|....:.|:.:..:
  Rat    44 FAFSLYKELVLKNPDKNIVFSSFSISTALVLLSLGAKNNTLKEILEGLKFNLTETPEAEIHQGYE 108

  Fly    98 QLLAKGQWEKASGDEDVPKLKYANRIFVTQRFKLTQTYQDLVSKNFAAAAENVNFTQKADTAKHI 162
            .||   |.....||:  .::...:.:|:.:..::...:|:.....:.|.|.:.:|.|..:..|.|
  Rat   109 HLL---QRLNLPGDQ--VQISTGSALFIKKHLQILAEFQEKARALYQAEAFSTDFQQPHEAKKLI 168

  Fly   163 NSWVEEQTHQQIKDLIAPESLDADTSAILVNAIYFKADWQSSFPDYATYASDFVNHGGRKVSVDT 227
            |.:|.:||..:||:||:  .||..||.:|||.||||..|:..|..:.|:.|:|.....:.|.|..
  Rat   169 NDYVRKQTQGKIKELIS--VLDKKTSMVLVNYIYFKGKWKMPFDPHDTFQSEFYLDEKKSVKVPM 231

  Fly   228 MSQE----DYFRFGELTELKAKVVELPYTGTDIVFLIILPQEEQG-LAIVEEKLMGIDLNEISSQ 287
            |..|    .|||.   .||...|:||.||| :...|.|||  :|| :..||..|....|......
  Rat   232 MKIEKLTTPYFRD---EELSCSVLELKYTG-NASALFILP--DQGRMQQVEASLQPETLRRWKDT 290

  Fly   288 LRRRKV-RVQLPKFKFEFDVPLQAALEELGIKKLFSPGANLSSLYQGSEPLRISEVKHKAIIEVN 351
            ||.|:: .:::|||....|:.|...|.||||:::||..|:||.: .|::.|.:|:|.|||:::|.
  Rat   291 LRPRRIDELRMPKFSISTDMRLGDILPELGIREVFSQQADLSRI-TGAKDLSVSQVVHKAVLDVT 354

  Fly   352 EKGTTASGATFIKVSVESLTIGEEVFEFIA---DHPFFFAIKDAQNT---LFLGHVS 402
            |.||.|:.||.:|:......     |.::.   :.||...|.|. ||   ||:..|:
  Rat   355 ETGTEAAAATGVKIIPMCAK-----FYYVTMYFNRPFLMIISDT-NTHIALFMAKVT 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42De	NP_610246.3	SERPIN	31..401	CDD:238101	127/379 (34%)
LOC100909605	XP_006240581.2	alpha-1-antitrypsin_like	41..404	CDD:239011	127/379 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010