DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42De and serpina10b

DIOPT Version :9

Sequence 1:	NP_610246.3	Gene:	Spn42De / 35602	FlyBaseID:	FBgn0033115	Length:	404	Species:	Drosophila melanogaster
Sequence 2:	XP_009291625.1	Gene:	serpina10b / 100003661	ZFINID:	ZDB-GENE-100716-5	Length:	395	Species:	Danio rerio

Alignment Length:	392	Identity:	117/392 - (29%)
Similarity:	197/392 - (50%)	Gaps:	38/392 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 NLAMANTLNYSKSPAGEAQFASQLFGQLAKSQSGRNIVFSPSSIRTGLALAYLGAEGSTADELKL 80
            :||..||           .||..|:.::: |...||:||||.|:.|..:...|.|:|||..|:..
Zfish    30 DLAFRNT-----------DFAINLYRKIS-SLHDRNVVFSPLSVSTCFSALLLAAQGSTRTEILK 82

  Fly    81 GLGLE---GAGKTEVAEKLDQLLAKGQWEKASGDEDVP-KLKYANRIFVTQRFKLTQTYQDLVSK 141
            ||.||   |.....|.|...||           .:::. :::....:|:.|.|.|...:...:.:
Zfish    83 GLNLEALDGGDSRRVPELFQQL-----------HQNISLQMEQGTALFLDQHFHLQTNFSQQIQR 136

  Fly   142 NFAAAAENVNFTQKADTAKHINSWVEEQTHQQIKDLIAPESLDADTSAILVNAIYFKADWQSSFP 206
            .|.|....|:|::.|.....||.:|..:|.:::.:::  ||::..|..:|:|.|::|.||:..|.
Zfish   137 FFNAEVLRVDFSKPAVCRSLINEFVSRKTGRKVLEML--ESVEPLTQMLLLNTIFYKGDWERPFN 199

  Fly   207 DYATYASDFVNHGGRKVSVDTMSQEDYFRFGELTELKAKVVELPYTGTDIVFLIILPQEEQGLAI 271
            ...|..|.|.......|.|..|..|:.|...|..:|:|:|:.|||.| ....||:||..:.....
Zfish   200 PNNTEKSRFYVDKYNIVQVPMMMLEEKFSVVEDRDLRARVLRLPYRG-GASMLILLPSADADYTA 263

  Fly   272 VEEKLMGIDLNEISSQLRRRKVRVQLPKFKFEFDVPLQAALEELGIKKLFSPGANLSSLYQGSEP 336
            :|:::....|:.....:||.|:.|.||:|:.:....:...|.:|||..:|...|:|:.|.:.:.
Zfish   264 IEDEISAERLHGWIKNMRRMKMEVHLPRFRMDQSYHMHELLPQLGISSVFQDSADLTGLSRDAH- 327

  Fly   337 LRISEVKHKAIIEVNEKGTTASGATFIKVSVESLTIGEEVFEFIADHPFFFAI--KDAQNTLFLG 399
            |::|:|.|||:|||.|:||:|:.:|.:.::..||.     ..||.:.||||.:  ::..:.||:|
Zfish   328 LKVSQVLHKAVIEVYEQGTSAASSTSVGITAYSLP-----DTFIINRPFFFFLYHEETASLLFMG 387

  Fly   400 HV 401
            .|
Zfish   388 RV 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42De	NP_610246.3	SERPIN	31..401	CDD:238101	112/375 (30%)
serpina10b	XP_009291625.1	Serpin	35..392	CDD:278507	115/387 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910