DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Dc and Serpinb9g

DIOPT Version :9

Sequence 1:	NP_001246154.1	Gene:	Spn42Dc / 35600	FlyBaseID:	FBgn0033113	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_035585.2	Gene:	Serpinb9g / 93806	MGIID:	1919260	Length:	377	Species:	Mus musculus

Alignment Length:	398	Identity:	124/398 - (31%)
Similarity:	205/398 - (51%)	Gaps:	39/398 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSEPQEGRNQFARNLIDVITKDALQQSKDPHINTVFSPASVQSALTLAFMGASGSTAEELRNGLQ 65
            |....:....||.:|:.|:.:|      :|..|..:||.|:.|||.:..:||.|.||.::...|.
Mouse     1 MDTLSQANGTFAIHLLKVLCQD------NPSKNVCYSPMSISSALAMVLLGAKGDTAVQICQALH 59

  Fly    66 LGPGDRHHIALNFGEFWRTSCNYGDRGPVLKSVNRLYVNDSLELLTEFNEIAVDFFQSKAEATRF 130
            |.|.:..|  ..|...........::...|...|||:|.::.|||..|.|..:.|:.|:.|...|
Mouse    60 LNPDEDVH--QGFQLLLHNLNKQNNQKYCLTMANRLFVENTCELLPTFKESCLKFYHSEMEQLSF 122

  Fly   131 AD-SEGATQLINDWVEQETEHKITNLLQSDAVNNETSALLINVLYFKGKWQKPFMPETTSIDHFH 194
            |: :|.:.|.||.||.::|..||.:||..|:||::|..:|.|.|||.|.|.|.|....|....|.
Mouse   123 AEAAEESRQHINMWVSKQTNGKIPDLLSKDSVNSQTRLILANALYFHGTWCKRFEKNRTKEMPFK 187

  Fly   195 VDRDTHVQVNMMYQEDKFRFAELPQLKARAVQLPYDYSNIHMLILLPNEVNGLQELEQQLNTVDL 259
            :::.....|.||::||....|.:.:::|:.:.:||:..:::.::|||:|            .||:
Mouse   188 INKKETRPVQMMWREDTLFHAYVKEIQAQVLVMPYEGIDLNFVVLLPDE------------GVDI 240

  Fly   260 ADIDAALTLQ--------------DVEIFLPRMCIEYDVDLKQVLNQLGITEVF-SDKAKLDGLF 309
            :.::..||.:              :..::||:..::.|.|:..:|..|||..|| ..||.|.|:.
Mouse   241 SKVENNLTFEKLTAWTKPEFMNRTEFHVYLPKFQLQEDYDMNSLLQHLGILNVFDGSKADLSGMS 305

  Fly   310 TSQSGQKISAARHRGYIDVNEAGSEAAAVSFMKIVPMMLNMNKKLFKADHPFVFYI--RNPQAVF 372
            |.:: ..:|...|:..::|||.|:||||.|.:|.:.:....:.:.|.|||||:|:|  |...::.
Mouse   306 TKEN-LCLSEFAHKCVVEVNEEGTEAAAASAVKFIFLCSGPDPETFCADHPFLFFIMHRTTNSIL 369

  Fly   373 FAGRFSNP 380
            |.||||:|
Mouse   370 FCGRFSSP 377

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dc	NP_001246154.1	SERPIN	7..377	CDD:238101	119/387 (31%)
Serpinb9g	NP_035585.2	SERPIN	4..377	CDD:294093	122/393 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	211	1.000	Domainoid score	I2787
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	215	1.000	Inparanoid score	I3599
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	1	1.000	-	-		otm44262
orthoMCL	1	0.900	-	-		OOG6_115848
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.780