DRSC/TRiP Functional Genomics Resources

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Protein Alignment Spn42Dc and SERPING1

DIOPT Version :9

Sequence 1:NP_001246154.1 Gene:Spn42Dc / 35600 FlyBaseID:FBgn0033113 Length:403 Species:Drosophila melanogaster
Sequence 2:NP_000053.2 Gene:SERPING1 / 710 HGNCID:1228 Length:500 Species:Homo sapiens


Alignment Length:380 Identity:106/380 - (27%)
Similarity:183/380 - (48%) Gaps:37/380 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly    15 LIDVITK--DALQQSKDPHINTVFSPASVQSALTLAFMGASGSTAEELRNGLQLGPGDRH--HIA 75
            |:|...|  .|....|....|..|||.|:.|.||...:||..:|...|.:.|.. |.|..  |.|
Human   146 LVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNLESILSY-PKDFTCVHQA 209

  Fly    76 LNFGEFWRTSCNYGDRGPVLKSVNRLYVNDSLELLTEFNEIAVDFFQSKAEATRFADSEGATQLI 140
            |.         .:..:|  :.||::::.:..|.:...|...:...:.|...... .:|:...:||
Human   210 LK---------GFTTKG--VTSVSQIFHSPDLAIRDTFVNASRTLYSSSPRVLS-NNSDANLELI 262

  Fly   141 NDWVEQETEHKITNLLQSDAVNNETSALLINVLYFKGKWQKPFMPETTSIDHFHVDRDTHVQVNM 205
            |.||.:.|.:||:.||  |::.::|..:|:|.:|...||:..|.|:.|.::.||. :::.::|.|
Human   263 NTWVAKNTNNKISRLL--DSLPSDTRLVLLNAIYLSAKWKTTFDPKKTRMEPFHF-KNSVIKVPM 324

  Fly   206 MYQEDKFRFAEL--PQLKARAVQLPYDYSNIHMLILLP-NEVNGLQELEQQLNTVDLADIDAALT 267
            | ...|:..|..  ..|||:..||...: |:.::||:| |..:.|:::||.|:......|...|.
Human   325 M-NSKKYPVAHFIDQTLKAKVGQLQLSH-NLSLVILVPQNLKHRLEDMEQALSPSVFKAIMEKLE 387

  Fly   268 L---QDVEIFLPRMCIEYDVDLKQVLNQLGITEVFSDKAKLDGLFTSQSGQKISAARHRGYIDVN 329
            :   |...:.|||:.:....|:..::.:|...: ||....|.|| |.....::||.:|:..:::.
Human   388 MSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFFD-FSYDLNLCGL-TEDPDLQVSAMQHQTVLELT 450

  Fly   330 EAGSEAAAVSFMKIVPMMLNMNKKLFKADHPFVFYIRNPQAVF--FAGRFSNPKS 382
            |.|.||||.|.:.:...:|     :|:...||:|.:.:.|..|  |.||..:|::
Human   451 ETGVEAAAASAISVARTLL-----VFEVQQPFLFVLWDQQHKFPVFMGRVYDPRA 500

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Spn42DcNP_001246154.1 SERPIN 7..377 CDD:238101 104/373 (28%)
SERPING1NP_000053.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 20..43
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 65..118
7 X 4 AA tandem repeats of [QE]-P-T-[TQ] 85..119
C1_inh 145..495 CDD:239005 104/373 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR11461
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
22.010

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