Protein Alignment Spn42Dc and Serpina12

DIOPT Version :10

• Sequence 1: NP_610245.2
• Gene: Spn42Dc / 35600
• FlyBaseID: FBgn0033113
• Length: 403
• Species: Drosophila melanogaster
• Sequence 2: NP_080811.1
• Gene: Serpina12 / 68054
• MGIID: 1915304
• Length: 413
• Species: Mus musculus
• Alignment Length: 395
• Identity: 118/395 - (29%)
• Similarity: 196/395 - (49%)
• Gaps: 39/395 - (9%)

  Fly     5 QEGR-----NQFARNLIDVITKDALQQ--SKDPHINTVFSPASVQSALTLAFMGASGSTAEELRN 62
            ||.|     .|.||:.::...| .||:  |..|..|...||.|:.:|.::..:||..||.||:|.
Mouse    37 QEWRGKKDARQLARHNMEFGFK-LLQRLASNSPQGNIFLSPLSISTAFSMLSLGAQNSTLEEIRE 100

  Fly    63 GL---QLGPGDRH---HIALN--FGEFWRTSCNYGDRGPVLKSVNRLYVNDSLELLTEFNEIAVD 119
            |.   ::...|.|   |..|:  ..|...|..|.|         |.|:::..|.....|..:|.:
Mouse   101 GFNFKEMSNWDVHAAFHYLLHKLNQETEDTKMNLG---------NALFMDQKLRPQQRFLNLAKN 156

  Fly   120 FFQSKAEATRFADSEGATQLINDWVEQETEHKITNLLQSDAVNNETSALLINVLYFKGKWQKPFM 184
            .:.:....|.|.|.|...:.||.::.|:|..:|.|:::|  ::..|..:|.|.:||:|:||..|.
Mouse   157 VYDADMVLTNFQDLENTQKDINRYISQKTHSRIKNMVKS--IDPGTVMILTNYIYFRGRWQYEFD 219

  Fly   185 PETTSIDHFHVDRDTHVQVNMMYQEDKFRFAELPQLKARAVQLPYDYSNIHMLILLPNEVNG-LQ 248
            |:.|..:.|.:::...|:|.||:|...:..|...||....:::|| ..||....:||:  || |:
Mouse   220 PKQTKEEEFFIEKGKTVKVPMMFQRGLYDMAYDSQLSCTILEIPY-RGNITATFVLPD--NGKLK 281

  Fly   249 ELEQQLNTVDLADIDAALTLQDVEIFLPRMCIEYDVDLKQVLNQLGITEVFSDKAKLDGLFTSQS 313
            .|||.|.....|...:.|:.:.|::::|::.|....::|:||::|||:::|.:...|..: :|..
Mouse   282 LLEQGLQADIFAKWKSLLSKRVVDVWVPKLRISSTYNMKKVLSRLGISKIFEENGDLTRI-SSHR 345

  Fly   314 GQKISAARHRGYIDVNEAGSEAAAVSFMKIVPMMLNMNKKLFKADHPFVFYIRN---PQAVFFAG 375
            ..|:..|.|:..:.::|.|.|.||.|..:.:||....:.||   |.||:..|..   |..||.|
Mouse   346 SLKVGEAVHKAELKMDEKGMEGAAGSGAQTLPMETPRHMKL---DRPFLMMIYENFMPSMVFLA- 406

  Fly   376 RFSNP 380
            |..:|
Mouse   407 RIYDP 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dc	NP_610245.2	serpin42Dd-like_insects	7..380	CDD:381070	115/391 (29%)
Serpina12	NP_080811.1	serpinA12_vaspin	40..411	CDD:381026	115/390 (29%)
		Reactive center loop. /evidence=ECO:0000250|UniProtKB:Q8IW75	364..382		7/17 (41%)