DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Dc and Serpini2

DIOPT Version :9

Sequence 1:	NP_001246154.1	Gene:	Spn42Dc / 35600	FlyBaseID:	FBgn0033113	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_080736.2	Gene:	Serpini2 / 67931	MGIID:	1915181	Length:	405	Species:	Mus musculus

Alignment Length:	377	Identity:	100/377 - (26%)
Similarity:	182/377 - (48%)	Gaps:	39/377 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 NTVFSPASVQSALTLAFMGASGSTAEELRNGLQLGPGDRHHIALNFGEFWRTSCNYGDRGPVLKS 97
            |.:|||......|.:..:||.|...:::...|::                 .....|:...||||
Mouse    44 NIIFSPLGTTMLLGMVQLGAKGKAQQQILKTLRM-----------------RGTPAGEEFSVLKS 91

  Fly    98 V----------------NRLYVNDSLELLTEFNEIAVDFFQSKAEATRFADSEGATQLINDWVEQ 146
            :                :.||:.:...:...:.....:||||..:...|.|::.:.|.|:.|||.
Mouse    92 LFSAISKKKQEFTFNLASALYLQEGFIVKETYLHSNKEFFQSATKLVDFLDAKTSAQAISTWVES 156

  Fly   147 ETEHKITNLLQSDAVNNETSALLINVLYFKGKWQKPFMPETTSIDHFHVDRDTHVQVNMMYQEDK 211
            :|:.||.|:...:.....|..:|:|.:||||.|::.|..|.|.:..|.....:.|:|.||....:
Mouse   157 KTDGKIKNMFSEEEFGPLTRLVLVNAIYFKGDWKQKFRKEDTEMTDFTKKDGSTVKVPMMKALLR 221

  Fly   212 FRFAELPQ--LKARAVQLPYDYSNIHMLILLPNEVNGLQELEQQLNTVDLADIDAALTLQDVEIF 274
            .::....|  :..:.::|||......::|:||.|...::|:|.|:....:....:.|..::||:.
Mouse   222 AQYGYFSQSSMTCQVLELPYKADEFSLVIILPTEDTSIEEVENQVTAPHVRRWFSELHEEEVEVS 286

  Fly   275 LPRMCIEYDVDLKQVLNQLGITEVFSDKAKLDGLFTSQSGQKISAARHRGYIDVNEAGSEAAAVS 339
            |||..||..:|||:.|..|.:||:||....|.|: |..|...:|....:.:.::||.||||||.:
Mouse   287 LPRFKIEQKLDLKEALYSLNVTEIFSGGCDLSGI-TDSSEVYVSRVMQKVFFEINEDGSEAAAST 350

  Fly   340 FMKIVPMMLNMNKKLFKADHPFVFYIRN--PQAVFFAGRFSNPKSGSGSGEE 389
            .:.| |.::::.:..|.|:|||:|.:::  .:::.|.|:.::|...:..|.:
Mouse   351 GINI-PAIMSLTQTQFLANHPFLFILKHIRTESILFMGKVTDPDIQTTKGRD 401

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dc	NP_001246154.1	SERPIN	7..377	CDD:238101	98/363 (27%)
Serpini2	NP_080736.2	neuroserpin	23..405	CDD:239003	100/377 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.030