Protein Alignment Spn42Dc and SERPINE3

DIOPT Version :10

• Sequence 1: NP_610245.2
• Gene: Spn42Dc / 35600
• FlyBaseID: FBgn0033113
• Length: 403
• Species: Drosophila melanogaster
• Sequence 2: NP_001094790.1
• Gene: SERPINE3 / 647174
• HGNCID: 24774
• Length: 424
• Species: Homo sapiens
• Alignment Length: 370
• Identity: 96/370 - (25%)
• Similarity: 164/370 - (44%)
• Gaps: 51/370 - (13%)

  Fly    33 NTVFSPASVQSALTLAFMGASGSTAEELRNGLQLGPGDRHHIALNFGEFWRTSCNYGDRGPVLKS 97
            |.|.|||.|...|.:...||.|||.::|.:.|.....|:.  ..:|......:.....:|..::.
Human    49 NFVISPAGVSLPLEILQFGAEGSTGQQLADALGYTVHDKR--VKDFLHAVYATLPTSSQGTEMEL 111

  Fly    98 VNRLYV------------------NDSLEL--LTEFNEIAVDFFQSKAEATRFADSEGATQLIND 142
            ...|:|                  |.|||.  |:|.|..|:   |:...|:|.....|.::....
Human   112 ACSLFVQVGTPLSPCFVEHVSWWANSSLEPADLSEPNSTAI---QTSEGASRETAGGGPSEGPGG 173

  Fly   143 WVEQETEHKITNLLQSDAVNNETSALLINVLYFKGKWQKPFMPETTSIDHFHVDRDTHVQVNMMY 207
            |..::.......|            :|::.:.|:|.|:|.|....|.|..|.......:||.||:
Human   174 WPWEQVSAAFAQL------------VLVSTMSFQGTWRKRFSSTDTQILPFTCAYGLVLQVPMMH 226

  Fly   208 QEDKFRFAELPQLKARAV---QLPYDYSNIHMLILLPNEVN-GLQELEQQLNTVDLADIDAALTL 268
            |..:..:.:........|   :|||..|.:.:.::||.:.: .|..:|..|....:.....:|..
Human   227 QTTEVNYGQFQDTAGHQVGVLELPYLGSAVSLFLVLPRDKDTPLSHIEPHLTASTIHLWTTSLRR 291

  Fly   269 QDVEIFLPRMCIEYDVDLKQVLNQLGITEVFSD-KAKLDGLFTSQSGQKISAARHRGYIDVNEAG 332
            ..:::||||..|:...:||.:||..|:|::|.. ||.|.|: :.|.|..:|.|.|:..|:|.|.|
Human   292 ARMDVFLPRFRIQNQFNLKSILNSWGVTDLFDPLKANLKGI-SGQDGFYVSEAIHKAKIEVLEEG 355

  Fly   333 SEAAAVSFMKIVPMMLNMNK-KLFKADHPFVFYIRNPQ---AVFF 373
            ::|:..:.:    ::|..:: .:||||.||::::|.|.   .|||
Human   356 TKASGATAL----LLLKRSRIPIFKADRPFIYFLREPNTGITVFF 396

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dc	NP_610245.2	serpin42Dd-like_insects	7..380	CDD:381070	96/370 (26%)
SERPINE3	NP_001094790.1	serpinE3	18..400	CDD:381040	96/370 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	143..174		8/33 (24%)