Protein Alignment Spn42Dc and SERPINE3

DIOPT Version :9

• Sequence 1: NP_001246154.1
• Gene: Spn42Dc / 35600
• FlyBaseID: FBgn0033113
• Length: 403
• Species: Drosophila melanogaster
• Sequence 2: NP_001094790.1
• Gene: SERPINE3 / 647174
• HGNCID: 24774
• Length: 424
• Species: Homo sapiens
• Alignment Length: 370
• Identity: 96/370 - (25%)
• Similarity: 164/370 - (44%)
• Gaps: 51/370 - (13%)

  Fly    33 NTVFSPASVQSALTLAFMGASGSTAEELRNGLQLGPGDRHHIALNFGEFWRTSCNYGDRGPVLKS 97
            |.|.|||.|...|.:...||.|||.::|.:.|.....|:.  ..:|......:.....:|..::.
Human    49 NFVISPAGVSLPLEILQFGAEGSTGQQLADALGYTVHDKR--VKDFLHAVYATLPTSSQGTEMEL 111

  Fly    98 VNRLYV------------------NDSLEL--LTEFNEIAVDFFQSKAEATRFADSEGATQLIND 142
            ...|:|                  |.|||.  |:|.|..|:   |:...|:|.....|.::....
Human   112 ACSLFVQVGTPLSPCFVEHVSWWANSSLEPADLSEPNSTAI---QTSEGASRETAGGGPSEGPGG 173

  Fly   143 WVEQETEHKITNLLQSDAVNNETSALLINVLYFKGKWQKPFMPETTSIDHFHVDRDTHVQVNMMY 207
            |..::.......|            :|::.:.|:|.|:|.|....|.|..|.......:||.||:
Human   174 WPWEQVSAAFAQL------------VLVSTMSFQGTWRKRFSSTDTQILPFTCAYGLVLQVPMMH 226

  Fly   208 QEDKFRFAELPQLKARAV---QLPYDYSNIHMLILLPNEVN-GLQELEQQLNTVDLADIDAALTL 268
            |..:..:.:........|   :|||..|.:.:.::||.:.: .|..:|..|....:.....:|..
Human   227 QTTEVNYGQFQDTAGHQVGVLELPYLGSAVSLFLVLPRDKDTPLSHIEPHLTASTIHLWTTSLRR 291

  Fly   269 QDVEIFLPRMCIEYDVDLKQVLNQLGITEVFSD-KAKLDGLFTSQSGQKISAARHRGYIDVNEAG 332
            ..:::||||..|:...:||.:||..|:|::|.. ||.|.|: :.|.|..:|.|.|:..|:|.|.|
Human   292 ARMDVFLPRFRIQNQFNLKSILNSWGVTDLFDPLKANLKGI-SGQDGFYVSEAIHKAKIEVLEEG 355

  Fly   333 SEAAAVSFMKIVPMMLNMNK-KLFKADHPFVFYIRNPQ---AVFF 373
            ::|:..:.:    ::|..:: .:||||.||::::|.|.   .|||
Human   356 TKASGATAL----LLLKRSRIPIFKADRPFIYFLREPNTGITVFF 396

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dc	NP_001246154.1	SERPIN	7..377	CDD:238101	96/370 (26%)
SERPINE3	NP_001094790.1	SERPIN	31..399	CDD:238101	96/370 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	143..174		8/33 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.020