Protein Alignment Spn42Dc and SERPINB4

DIOPT Version :9

• Sequence 1: NP_001246154.1
• Gene: Spn42Dc / 35600
• FlyBaseID: FBgn0033113
• Length: 403
• Species: Drosophila melanogaster
• Sequence 2: NP_002965.1
• Gene: SERPINB4 / 6318
• HGNCID: 10570
• Length: 390
• Species: Homo sapiens
• Alignment Length: 395
• Identity: 125/395 - (31%)
• Similarity: 211/395 - (53%)
• Gaps: 35/395 - (8%)

  Fly    14 NLIDVITK---DALQQSKDPHINTVF-SPASVQSALTLAFMGASGSTAEELRNGLQLG------- 67
            :|.:..||   |..||.:....|.:| ||.|:.|||.:..:||..:||:::...|...
Human     3 SLSEANTKFMFDLFQQFRKSKENNIFYSPISITSALGMVLLGAKDNTAQQISKVLHFDQVTENTT 67

  Fly    68 ----------PGDRHHIALNFGEFWR--TSCNYGDRGPVLKSVNRLYVNDSLELLTEFNEIAVDF 120
                      .|:.||      :|.:  |..|.......||..|:|:...:.:.|.|:.:....|
Human    68 EKAATYHVDRSGNVHH------QFQKLLTEFNKSTDAYELKIANKLFGEKTYQFLQEYLDAIKKF 126

  Fly   121 FQSKAEATRFADS-EGATQLINDWVEQETEHKITNLLQSDAVNNETSALLINVLYFKGKWQKPFM 184
            :|:..|:|.||:: |.:.:.||.|||.:|..||.||.....:.|:|:.:|:|.:||||:|:..|.
Human   127 YQTSVESTDFANAPEESRKKINSWVESQTNEKIKNLFPDGTIGNDTTLVLVNAIYFKGQWENKFK 191

  Fly   185 PETTSIDHFHVDRDTHVQVNMMYQEDKFRFAELPQLKARAVQLPYDYSNIHMLILLPNEVNGLQE 249
            .|.|..:.|..:::|:..|.||.|.:.|.||.|..::|:.:::||...::.|::|||||::|||:
Human   192 KENTKEEKFWPNKNTYKSVQMMRQYNSFNFALLEDVQAKVLEIPYKGKDLSMIVLLPNEIDGLQK 256

  Fly   250 LEQQLNTVDLADIDAALTLQD--VEIFLPRMCIEYDVDLKQVLNQLGITEVFSDKAKLDGLFTSQ 312
            ||::|....|.:..:...:::  |::.|||..:|...|||..|..:|:..:|:..|.|.|: |..
Human   257 LEEKLTAEKLMEWTSLQNMRETCVDLHLPRFKMEESYDLKDTLRTMGMVNIFNGDADLSGM-TWS 320

  Fly   313 SGQKISAARHRGYIDVNEAGSEAAAVSFMKIVPMMLNMNKKLFKADHPFVFYIR--NPQAVFFAG 375
            .|..:|...|:.:::|.|.|.||||.:.:.:|.:......:.|..:|||:|:||  ...::.|.|
Human   321 HGLSVSKVLHKAFVEVTEEGVEAAAATAVVVVELSSPSTNEEFCCNHPFLFFIRQNKTNSILFYG 385

  Fly   376 RFSNP 380
            |||:|
Human   386 RFSSP 390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dc	NP_001246154.1	SERPIN	7..377	CDD:238101	121/390 (31%)
SERPINB4	NP_002965.1	SERPIN	4..390	CDD:320777	124/392 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	1	1.000	-	-		mtm8652
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.930