Protein Alignment Spn42Dc and SERPINB3

DIOPT Version :9

• Sequence 1: NP_001246154.1
• Gene: Spn42Dc / 35600
• FlyBaseID: FBgn0033113
• Length: 403
• Species: Drosophila melanogaster
• Sequence 2: NP_008850.1
• Gene: SERPINB3 / 6317
• HGNCID: 10569
• Length: 390
• Species: Homo sapiens
• Alignment Length: 395
• Identity: 122/395 - (30%)
• Similarity: 209/395 - (52%)
• Gaps: 35/395 - (8%)

  Fly    14 NLIDVITK---DALQQSKDPHINTVF-SPASVQSALTLAFMGASGSTAEELRNGLQLG------- 67
            :|.:..||   |..||.:....|.:| ||.|:.|||.:..:||..:||::::..|...
Human     3 SLSEANTKFMFDLFQQFRKSKENNIFYSPISITSALGMVLLGAKDNTAQQIKKVLHFDQVTENTT 67

  Fly    68 ----------PGDRHHIALNFGEFWR--TSCNYGDRGPVLKSVNRLYVNDSLELLTEFNEIAVDF 120
                      .|:.||      :|.:  |..|.......||..|:|:...:...|.|:.:....|
Human    68 GKAATYHVDRSGNVHH------QFQKLLTEFNKSTDAYELKIANKLFGEKTYLFLQEYLDAIKKF 126

  Fly   121 FQSKAEATRFADS-EGATQLINDWVEQETEHKITNLLQSDAVNNETSALLINVLYFKGKWQKPFM 184
            :|:..|:..||:: |.:.:.||.|||.:|..||.||:....:.:.|:.:|:|.:||||:|:|.|.
Human   127 YQTSVESVDFANAPEESRKKINSWVESQTNEKIKNLIPEGNIGSNTTLVLVNAIYFKGQWEKKFN 191

  Fly   185 PETTSIDHFHVDRDTHVQVNMMYQEDKFRFAELPQLKARAVQLPYDYSNIHMLILLPNEVNGLQE 249
            .|.|..:.|..:::|:..:.||.|...|.||.|..::|:.:::||...::.|::|||||::|||:
Human   192 KEDTKEEKFWPNKNTYKSIQMMRQYTSFHFASLEDVQAKVLEIPYKGKDLSMIVLLPNEIDGLQK 256

  Fly   250 LEQQLNTVDLADIDAALTLQD--VEIFLPRMCIEYDVDLKQVLNQLGITEVFSDKAKLDGLFTSQ 312
            ||::|....|.:..:...:::  |::.|||..:|...|||..|..:|:.::|:..|.|.|: |..
Human   257 LEEKLTAEKLMEWTSLQNMRETRVDLHLPRFKVEESYDLKDTLRTMGMVDIFNGDADLSGM-TGS 320

  Fly   313 SGQKISAARHRGYIDVNEAGSEAAAVSFMKIVPMMLNMNKKLFKADHPFVFYIR--NPQAVFFAG 375
            .|..:|...|:.:::|.|.|:||||.:.:...........:.|..:|||:|:||  ...::.|.|
Human   321 RGLVLSGVLHKAFVEVTEEGAEAAAATAVVGFGSSPTSTNEEFHCNHPFLFFIRQNKTNSILFYG 385

  Fly   376 RFSNP 380
            |||:|
Human   386 RFSSP 390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dc	NP_001246154.1	SERPIN	7..377	CDD:238101	118/390 (30%)
SERPINB3	NP_008850.1	serpinB3_B4_SCCA1_2	1..390	CDD:381030	121/393 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	1	1.000	-	-		mtm8652
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.830