DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Dc and serping1

DIOPT Version :9

Sequence 1:	NP_001246154.1	Gene:	Spn42Dc / 35600	FlyBaseID:	FBgn0033113	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	XP_005166940.3	Gene:	serping1 / 567801	ZFINID:	ZDB-GENE-030131-1262	Length:	652	Species:	Danio rerio

Alignment Length:	404	Identity:	107/404 - (26%)
Similarity:	175/404 - (43%)	Gaps:	72/404 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 QEGRNQFARNLIDVITKDALQQSKDPHINTVFSPASVQSALTLAFMGASGSTAEELRN--GLQLG 67
            ||....|:.::.     ..|:.|| ...|.:|||.|:.:||:...:||.|.|...|..  ||.||
Zfish   293 QESLGDFSTSVY-----SRLKGSK-AKANLIFSPISIAAALSNLLLGARGKTRMHLEGALGLPLG 351

  Fly    68 PGDRHHIALNFGEFWRTSCNYGD----RG---PVLKSVNRLYVNDSLELLTEFNEIAVDFFQSKA 125
                            .||.:.:    ||   ..||..:.::.|...:|...|...:.:|::...
Zfish   352 ----------------FSCLHTELKKLRGVMKDTLKMASAIFYNPEQQLAEAFINQSKEFYEFVP 400

  Fly   126 EATRFADSEGATQLINDWVEQETEHKITNLLQSDAVNNETSALLINVLYFKGKWQKPFMPETTSI 190
            :... .||.....|||.|||.:|..|||.|:  |.|:..|:.:|:|.:||.|||:..| ..|.:.
Zfish   401 QKLT-NDSTRNVALINKWVENKTNKKITQLI--DDVDPSTTFVLLNAVYFNGKWKTVF-ESTNNK 461

  Fly   191 DHFHVDRDTHVQVNMMYQEDK-FRFAELPQLKARAVQLPYDYSN-IHMLI----------LLPNE 243
            :.|.:.......|..:|..:. .:.....||||...:.|....| :::|:          |:.|.
Zfish   462 EKFTMFSGETKDVKTLYSSNYILQMGYNKQLKADVGKFPLTGQNSLYILVPRTLSEESFLLMENN 526

  Fly   244 V--NGLQELEQQLNTVDLADIDAALTLQDVEIFLPRMCIEYDVDLKQVLNQLGITEVFSDKAKLD 306
            :  |.|:|:..::|..         ..|..|:.||.:.:.....:..:|..:|::::|:: ..|.
Zfish   527 INRNTLEEMVSEMNQT---------PAQSAEVTLPAIKLTMTTQVDDLLRNMGLSDLFNN-PNLC 581

  Fly   307 GLFTSQSGQKISAARHRGYIDVNEAGSEAAA---VSFMKIVPMMLNMNKKLFKADHPFVFYIRNP 368
            |:|..:....||..|||.::.:.|.|.||||   :||.:        :...|.|..|||..:.:.
Zfish   582 GMFPGEPESFISDVRHRAFLSLTEKGVEAAAATSISFSR--------SFSSFSALQPFVLILWSD 638

  Fly   369 QAV--FFAGRFSNP 380
            :|.  .|.||..||
Zfish   639 EAAVPLFMGRIINP 652

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dc	NP_001246154.1	SERPIN	7..377	CDD:238101	102/397 (26%)
serping1	XP_005166940.3	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010