DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Dc and serpini1

DIOPT Version :9

Sequence 1:	NP_001246154.1	Gene:	Spn42Dc / 35600	FlyBaseID:	FBgn0033113	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_001122164.1	Gene:	serpini1 / 557627	ZFINID:	ZDB-GENE-060503-390	Length:	415	Species:	Danio rerio

Alignment Length:	364	Identity:	113/364 - (31%)
Similarity:	184/364 - (50%)	Gaps:	21/364 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 NTVFSPASVQSALTLAFMGASGSTAEELRNGL---QLGPGDRHHIALNFGEFWRTSCNYGDRGPV 94
            |.:|||.||..||.:..:||.||:.:|:|..:   .....:...:..|..:...|.    :...|
Zfish    47 NIIFSPLSVALALGMVELGARGSSLQEIRQAVGYSHFREDEEFSLLRNLSQALSTD----EEQYV 107

  Fly    95 LKSVNRLYVNDSLELLTEFNEIAVDFFQSKAEATRFADSEGATQLINDWVEQETEHKITNLLQSD 159
            ::..|.|::...:....:|.::...:|:::.|...|:.|....:.||.||...||.||.||:.::
Zfish   108 VRLANSLFLQSGVHFNEDFLQLMKKYFRAEVETVDFSQSTAVAERINSWVLNHTESKIQNLVSAE 172

  Fly   160 AVNNETSALLINVLYFKGKWQKPFMPETTSIDHFHVDRDTHVQVNMMYQEDKFRFAELPQLKARA 224
            ..::.|..:|:|.:||:|.|:..|.||.|....|..|..:.||..||||:..|.:.|.......|
Zfish   173 DFSSSTMIMLVNAVYFRGSWKNQFRPENTRTFSFTRDDGSEVQTLMMYQQGDFYYGEFSDGTTEA 237

  Fly   225 ------VQLPYDYSNIHMLILLPNEVNGLQELEQQLNTVDLADIDAALTLQDVEIFLPRMCIEYD 283
                  :::.|:..::.|:|:||.:...|..||..:....|.:....:..|.||::|||..:|..
Zfish   238 GGVYQVLEMLYEGEDMSMMIVLPRQEVPLASLEPIIKAPLLEEWANNVKRQKVEVYLPRFKVEQK 302

  Fly   284 VDLKQVLNQLGITEVFSDKAKLDGLFTSQ--SGQK--ISAARHRGYIDVNEAGSEAAAVSFMKIV 344
            :||::.|.||||..:||..|.|..: |:|  .||.  |..|..:.|::|.|.|:|.||.|.|..:
Zfish   303 IDLRESLQQLGIRSIFSKDADLSAM-TAQMTDGQDLFIGKAVQKAYLEVTEEGAEGAAGSGMIAL 366

  Fly   345 PMMLNMNKKLFKADHPFVFYIRNPQ--AVFFAGRFSNPK 381
            ...|.:..::. |||||.|.|||.:  ::.|.||..||:
Zfish   367 TRTLVLYPQVM-ADHPFFFIIRNRKTGSILFMGRVMNPE 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dc	NP_001246154.1	SERPIN	7..377	CDD:238101	110/358 (31%)
serpini1	NP_001122164.1	SERPIN	25..414	CDD:294093	113/364 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	1	1.000	-	-		mtm6540
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	8.030