DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Dc and serpine3

DIOPT Version :9

Sequence 1:	NP_001246154.1	Gene:	Spn42Dc / 35600	FlyBaseID:	FBgn0033113	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_001116709.1	Gene:	serpine3 / 556612	ZFINID:	ZDB-GENE-050309-223	Length:	417	Species:	Danio rerio

Alignment Length:	401	Identity:	112/401 - (27%)
Similarity:	192/401 - (47%)	Gaps:	53/401 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 QFARNLIDVITKDALQQSKDPHINTVFSPASVQSALTLAFMGASGSTAEELRNGLQLGPGD---R 71
            ||..:|...:|:   .::|.   |.:.|||||...|.|..:||.|:|..:|...|.....|   :
Zfish    36 QFGISLYQTLTE---TENKS---NLIVSPASVSLCLGLLQLGARGNTLVQLEGTLGYDVNDVRVQ 94

  Fly    72 HHIALNFGEFWRTSCNYGDRGPVLKSVNRLYVNDSLELLTEFNEIAVDFFQSKAEATRFADSEGA 136
            :.::...|:...:|     .|..|:..|.|::...::||.||.:.|:.:..:...:..|::....
Zfish    95 NILSRPQGDLANSS-----EGLRLQLANALFIQTGVKLLPEFTQHALGWGNTSLLSVNFSNPNHT 154

  Fly   137 TQLINDWVEQET---EHKIT--NLLQSDAVNNETS-------ALLINVLYFKGKWQKPFM-PETT 188
            ...:..|...::   :|..|  .|..|.....|.:       ..|::.|.|.|.|||.|: .||.
Zfish   155 HSRLQQWAHYQSKADDHLQTREELHHSSGEEEEATRQDHLLYMALVSTLVFHGAWQKQFLFTETQ 219

  Fly   189 SIDHFHVDRDTHVQVNMMYQEDKFRFA--ELP-QLKARAVQLPYDYSNIHMLILLPNE-VNGLQE 249
            ::.....|..| |:|.||||..:....  .|| :.:...::|||...::.:|:.||:: ...|.:
Zfish   220 NLPFTFSDGST-VKVPMMYQSSEVNIGHFRLPSEQEYTVLELPYLDHSLRLLVALPSDRKTPLSQ 283

  Fly   250 LEQQLNTVDLADIDAALTLQDVEIFLPRMCIEYDVDLKQVLNQLGITEVFSDKA-------KLDG 307
            ||:|:....:...|..|....::|||||..::..::||.||..||::::||..|       ..||
Zfish   284 LEKQITARAVGLWDTGLRRTKMDIFLPRFKMQSKINLKPVLQSLGVSDIFSPSAADFRGISDTDG 348

  Fly   308 LFTSQSGQKISAARHRGYIDVNEAGSEAAAVSFMKIVPMMLNMNKK-LFKADHPFVFYIR--NPQ 369
            :|       :|.|.|...|:|.|||::||:.:.|    ::|..::. :||||.||:|.:|  :..
Zfish   349 IF-------VSEAFHEARIEVTEAGTKAASATAM----VLLKRSRSAVFKADRPFLFILRQISTG 402

  Fly   370 AVFFAGRFSNP 380
            ::.|.||..||
Zfish   403 SLLFIGRVVNP 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dc	NP_001246154.1	SERPIN	7..377	CDD:238101	109/396 (28%)
serpine3	NP_001116709.1	Serpin	35..413	CDD:278507	110/399 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.110