DRSC/TRiP Functional Genomics Resources

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Protein Alignment Spn42Dc and SERPINB13

DIOPT Version :10

Sequence 1:NP_610245.2 Gene:Spn42Dc / 35600 FlyBaseID:FBgn0033113 Length:403 Species:Drosophila melanogaster
Sequence 2:NP_001294852.1 Gene:SERPINB13 / 5275 HGNCID:8944 Length:400 Species:Homo sapiens


Alignment Length:393 Identity:106/393 - (26%)
Similarity:196/393 - (49%) Gaps:47/393 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly    24 LQQSKDPHINTVFSPASVQSALTLAFMGASGSTAEELR--------------------------N 62
            |:::.|.  |..|||..:.:|:.:..:|..|:||.:|.                          .
Human    19 LKKTNDG--NIFFSPVGILTAIGMVLLGTRGATASQLEEVFHSEKETKSSRIKAEEKEVVRIKAE 81

  Fly    63 GLQLGPGDRHHIALNFGEFWRTSCNYGDRGPVLKSVNRLYVNDSLELLTEFNEIAVDFFQSKAEA 127
            |.::...:..|  ..|.:| .|..:.......|...|||:...:...|.::.:....::.:..|.
Human    82 GKEIENTEAVH--QQFQKF-LTEISKLTNDYELNITNRLFGEKTYLFLQKYLDYVEKYYHASLEP 143

  Fly   128 TRFAD-SEGATQLINDWVEQETEHKITNLLQSDAVNNETSALLINVLYFKGKWQKPFMPETTSID 191
            ..|.: ::.:.:.||.|||.:|..||.:|....::::.|..:|:|::||||:|.:.|..|.|..:
Human   144 VDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVNMVYFKGQWDREFKKENTKEE 208

  Fly   192 HFHVDRDTHVQVNMMYQEDKFRFAELPQLKARAVQLPYDYSNIHMLILLPNEVNGLQELEQQLNT 256
            .|.:::.|...|.||.|...|.|..|..|:|:.:.:||..:::.|.:||||:::||:::..:::.
Human   209 KFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIPYKNNDLSMFVLLPNDIDGLEKIIDKISP 273

  Fly   257 VDLADIDAALTLQD--VEIFLPRMCIEYDVDLKQVLNQLGITEVFSD-KAKLDGLFTSQSGQKIS 318
            ..|.:..:...:::  |.:.|||..:|...||:.||..:|:.:.||: ||...|: :|.||....
Human   274 EKLVEWTSPGHMEERKVNLHLPRFEVEDGYDLEAVLAAMGMGDAFSEHKADYSGM-SSGSGLYAQ 337

  Fly   319 AARHRGYIDVNEAGSEAAA---VSF-MKIVPMMLNMNKKLFKADHPFVFYIRNPQ--AVFFAGRF 377
            ...|..::.|.|.|:||||   :.| :...|...|::     .:|||:|:||:.:  ::.|.|||
Human   338 KFLHSSFVAVTEEGTEAAAATGIGFTVTSAPGHENVH-----CNHPFLFFIRHNESNSILFFGRF 397

  Fly   378 SNP 380
            |:|
Human   398 SSP 400

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Spn42DcNP_610245.2 serpin42Dd-like_insects 7..380 CDD:381070 105/391 (27%)
SERPINB13NP_001294852.1 serpinB13_headpin 1..400 CDD:381038 105/391 (27%)

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