Protein Alignment Spn42Dc and SERPINB10

DIOPT Version :9

• Sequence 1: NP_001246154.1
• Gene: Spn42Dc / 35600
• FlyBaseID: FBgn0033113
• Length: 403
• Species: Drosophila melanogaster
• Sequence 2: NP_005015.1
• Gene: SERPINB10 / 5273
• HGNCID: 8942
• Length: 397
• Species: Homo sapiens
• Alignment Length: 405
• Identity: 121/405 - (29%)
• Similarity: 209/405 - (51%)
• Gaps: 49/405 - (12%)

  Fly     9 NQFARNLIDVITKDALQQSKDPHINTVFSPASVQSALTLAFMGASGSTAEELR--------NGLQ 65
            ||||..|...:.:.|  |.|    |..||..|:.::||:.::||.|:||.::.        .|::
Human     9 NQFALELSKKLAESA--QGK----NIFFSSWSISTSLTIVYLGAKGTTAAQMAQVLQFNRDQGVK 67

  Fly    66 LGPGDRHHIALNF----------------GEFWRTSCNYGDRGPVLKSVNRLYVNDSLELLTEFN 114
            ..|.......:.|                .|..:.:.:|     :||:.|.:|...:.....::.
Human    68 CDPESEKKRKMEFNLSNSEEIHSDFQTLISEILKPNDDY-----LLKTANAIYGEKTYAFHNKYL 127

  Fly   115 EIAVDFFQSKAEATRFAD-SEGATQLINDWVEQETEHKITNLLQSDAVNNETSALLINVLYFKGK 178
            |....:|.::.:...|.: |:...:.||.|||::||.||.|||..|:|::.|..:|:|.|||||.
Human   128 EDMKTYFGAEPQPVNFVEASDQIRKDINSWVERQTEGKIQNLLPDDSVDSTTRMILVNALYFKGI 192

  Fly   179 WQKPFMPETTSIDHFHVDRDTHVQVNMMYQEDKFRFAELPQLKARAVQLPYDYSNIHMLILLPNE 243
            |:..|:.:.|:...|.::..|...|.||:.:.|.....:.:.||..:||.|...::.:|||||.:
Human   193 WEHQFLVQNTTEKPFRINETTSKPVQMMFMKKKLHIFHIEKPKAVGLQLYYKSRDLSLLILLPED 257

  Fly   244 VNGLQELE-----QQLNTVDLADIDAALTLQDVEIFLPRMCIEYDVDLKQVLNQLGITEVFS-DK 302
            :|||::||     ::||....||:   :.|.:|::.||:..:|...|||..|:.:|:::.|| .|
Human   258 INGLEQLEKAITYEKLNEWTSADM---MELYEVQLHLPKFKLEDSYDLKSTLSSMGMSDAFSQSK 319

  Fly   303 AKLDGLFTSQSGQKISAARHRGYIDVNEAGSEAAAVSFMKIVPMMLNMNKKLFKADHPFVFYIRN 367
            |...|: :|.....:|...|:.::::||.|:||||.|..:| .:.:.:....|.|:|||:|:||:
Human   320 ADFSGM-SSARNLFLSNVFHKAFVEINEQGTEAAAGSGSEI-DIRIRVPSIEFNANHPFLFFIRH 382

  Fly   368 --PQAVFFAGRFSNP 380
              ...:.|.||..:|
Human   383 NKTNTILFYGRLCSP 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dc	NP_001246154.1	SERPIN	7..377	CDD:238101	119/400 (30%)
SERPINB10	NP_005015.1	PAI-2	4..397	CDD:239013	120/403 (30%)
		Nuclear localization signal	74..77		0/2 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	1	1.000	-	-		mtm8652
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.930