Protein Alignment Spn42Dc and SERPINB8

DIOPT Version :9

• Sequence 1: NP_001246154.1
• Gene: Spn42Dc / 35600
• FlyBaseID: FBgn0033113
• Length: 403
• Species: Drosophila melanogaster
• Sequence 2: NP_001353127.1
• Gene: SERPINB8 / 5271
• HGNCID: 8952
• Length: 374
• Species: Homo sapiens
• Alignment Length: 402
• Identity: 135/402 - (33%)
• Similarity: 210/402 - (52%)
• Gaps: 50/402 - (12%)

  Fly     1 MSEPQEGRNQFARNLIDVITKDALQQSKDPHINTVFSPASVQSALTLAFMGASGSTAEELRNGLQ 65
            |.:..|....||.:|..::.::      |...|..|||.|:.|||.:.||||.||||.::...|.
Human     1 MDDLCEANGTFAISLFKILGEE------DNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALC 59

  Fly    66 L-GPGDRHH-IALNFGEFWRTSCNYGDRGPVLKSVNRLYVNDSLELLTEFNEIAVDFFQSKAEAT 128
            | ..||.|. ......|..||...|     :|::.|||:...:.:.|.:|.|....|:|::.|..
Human    60 LYKDGDIHRGFQSLLSEVNRTGTQY-----LLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEEL 119

  Fly   129 RFA-DSEGATQLINDWVEQETEHKITNLLQSDAVNNETSALLINVLYFKGKWQKPFMPETTSIDH 192
            .|| |:|...:.|||||.::||.||:.:|.:..|:..|..:|:|.:||||||.:.|..:.|....
Human   120 SFAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGML 184

  Fly   193 FHVDRDTHVQVNMMYQEDKFRFAELPQLKARAVQLPYDYSNIHMLILLPNEVNGLQELEQQLNTV 257
            |..:.:... |.||::|.||:.....::..:.::|||....:.|:||||::           ||
Human   185 FKTNEEKKT-VQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDD-----------NT- 236

  Fly   258 DLADIDAALTLQ--------------DVEIFLPRMCIEYDVDLKQVLNQLGITEVFSDKAKLDGL 308
            |||.::.|||.:              .|::||||:.:|...||:..|.:||:.:.| |:||.|
Human   237 DLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAF-DEAKAD-- 298

  Fly   309 FTSQSGQK---ISAARHRGYIDVNEAGSEAAAVSFMKIVPMMLNMNKKLFKADHPFVFYIRN--P 368
            |:..|.:|   :|...|:.:::|||.|:||||.:.:........|..: |.|||||:|:||:  .
Human   299 FSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPR-FCADHPFLFFIRHHKT 362

  Fly   369 QAVFFAGRFSNP 380
            ..:.|.||||:|
Human   363 NCILFCGRFSSP 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dc	NP_001246154.1	SERPIN	7..377	CDD:238101	129/391 (33%)
SERPINB8	NP_001353127.1	SERPIN	4..374	CDD:320777	133/397 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	1	1.000	-	-		mtm8652
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.930