Protein Alignment Spn42Dc and SERPINE2

DIOPT Version :10

• Sequence 1: NP_610245.2
• Gene: Spn42Dc / 35600
• FlyBaseID: FBgn0033113
• Length: 403
• Species: Drosophila melanogaster
• Sequence 2: XP_005246698.1
• Gene: SERPINE2 / 5270
• HGNCID: 8951
• Length: 410
• Species: Homo sapiens
• Alignment Length: 377
• Identity: 109/377 - (28%)
• Similarity: 167/377 - (44%)
• Gaps: 51/377 - (13%)

  Fly    30 PHINTVFSPASVQSALTLAFMGASGSTAEELRNGLQLGPGDRHHIALNFGEFWRTSCNYGDRGPV 94
            ||.|.|.||..:.|.|.:..:||.|.|.::|...::.|                    ....|.:
Human    59 PHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYG--------------------VNGVGKI 103

  Fly    95 LKSVNRLYVN-DSLELLTEFNEIAV---------------DFFQSKAEATRFADSEGATQLINDW 143
            ||.:|:..|: .:.:::|..|.:.|               |.||.:.....|.|...|...||.|
Human   104 LKKINKAIVSKKNKDIVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAW 168

  Fly   144 VEQETEHKITNLLQSDAVNNE-TSALLINVLYFKGKWQKPFMPETTSIDHFHVDRDTHVQVNMMY 207
            |:.||...|.|||..|.::.. |..:|:|.:||||.|:..|.||.|....|........||.|:.
Human   169 VKNETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLA 233

  Fly   208 QEDKFRFAELP---QLKARAVQLPYDYSNIHMLILLPNEVNGLQELEQQLNTVDLADIDAALTL- 268
            |...||.....   .|....::|||...:|.|||.||.|.:  ..|...:..:....||:.:::
Human   234 QLSVFRCGSTSAPNDLWYNFIELPYHGESISMLIALPTESS--TPLSAIIPHISTKTIDSWMSIM 296

  Fly   269 --QDVEIFLPRMCIEYDVDLKQVLNQLGITEVF-SDKAKLDGLFTSQSGQKISAARHRGYIDVNE 330
              :.|::.||:.......|||:.|..||||::| |.||....:.|......:|....:..|:|:|
Human   297 VPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITTGSENLHVSHILQKAKIEVSE 361

  Fly   331 AGSEAAAVSFMKIVPMMLNMNKKLFKADHPFVFYIR-NPQ-AVFFAGRFSNP 380
            .|::|:|.:   ...::...:...|..|.||:|:|| ||. ||.|.|:.:.|
Human   362 DGTKASAAT---TAILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dc	NP_610245.2	serpin42Dd-like_insects	7..380	CDD:381070	108/375 (29%)
SERPINE2	XP_005246698.1	serpinE2_GDN	33..408	CDD:381039	108/373 (29%)