Protein Alignment Spn42Dc and SERPINA1

DIOPT Version :9

• Sequence 1: NP_001246154.1
• Gene: Spn42Dc / 35600
• FlyBaseID: FBgn0033113
• Length: 403
• Species: Drosophila melanogaster
• Sequence 2: NP_000286.3
• Gene: SERPINA1 / 5265
• HGNCID: 8941
• Length: 418
• Species: Homo sapiens
• Alignment Length: 384
• Identity: 126/384 - (32%)
• Similarity: 200/384 - (52%)
• Gaps: 28/384 - (7%)

  Fly     9 NQFARNLIDV---ITKDALQQSKDPHINTVFSPASVQSALTLAFMGASGSTAEELRNGLQLG--- 67
            |:...||.:.   :.:....||..  .|..|||.|:.:|..:..:|....|.:|:..||...
Human    48 NKITPNLAEFAFSLYRQLAHQSNS--TNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTE 110

  Fly    68 -PGDRHHIALNFGEFWRTSCNYGDRGPVLKSVNRLYVNDSLELLTEFNEIAVDFFQSKAEATRFA 131
             |..:.|  ..|.|..|| .|..|....|.:.|.|::::.|:|:.:|.|.....:.|:|....|.
Human   111 IPEAQIH--EGFQELLRT-LNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFG 172

  Fly   132 DSEGATQLINDWVEQETEHKITNLLQSDAVNNETSALLINVLYFKGKWQKPFMPETTSIDHFHVD 196
            |:|.|.:.|||:||:.|:.||.:|::.  ::.:|...|:|.::|||||::||..:.|..:.||||
Human   173 DTEEAKKQINDYVEKGTQGKIVDLVKE--LDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVD 235

  Fly   197 RDTHVQVNMMYQEDKFRFAELPQLKARAVQLPYDYSNIHMLILLPNEVNGLQELEQQLNTVDLAD 261
            :.|.|:|.||.:...|......:|.:..:.:.| ..|...:..||:| ..||.||.:| |.|:
Human   236 QVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKY-LGNATAIFFLPDE-GKLQHLENEL-THDI-- 295

  Fly   262 IDAALTLQD---VEIFLPRMCIEYDVDLKQVLNQLGITEVFSDKAKLDGLFTSQSGQKISAARHR 323
            |...|..:|   ..:.||::.|....|||.||.|||||:|||:.|.|.|: |.::..|:|.|.|:
Human   296 ITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGV-TEEAPLKLSKAVHK 359

  Fly   324 GYIDVNEAGSEAAAVSFMKIVPMMLNMNKKLFKADHPFVFYI--RNPQAVFFAGRFSNP 380
            ..:.::|.|:|||...|::.:||.:....|..|   ||||.:  :|.::..|.|:..||
Human   360 AVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNK---PFVFLMIEQNTKSPLFMGKVVNP 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dc	NP_001246154.1	SERPIN	7..377	CDD:238101	124/379 (33%)
SERPINA1	NP_000286.3	alpha-1-antitrypsin_like	55..412	CDD:239011	121/372 (33%)
		RCL	368..392		8/23 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.010