Protein Alignment Spn42Dc and SERPINB2

DIOPT Version :9

• Sequence 1: NP_001246154.1
• Gene: Spn42Dc / 35600
• FlyBaseID: FBgn0033113
• Length: 403
• Species: Drosophila melanogaster
• Sequence 2: NP_001137290.1
• Gene: SERPINB2 / 5055
• HGNCID: 8584
• Length: 415
• Species: Homo sapiens
• Alignment Length: 422
• Identity: 118/422 - (27%)
• Similarity: 198/422 - (46%)
• Gaps: 69/422 - (16%)

  Fly    11 FARNLIDVITKDALQQSKDPHINTVFSPASVQSALTLAFMGASGSTAEELRNGLQLGPGDRHHIA 75
            ||.||...:.|      ..|..|...||.|:.|.:.:.:||:.|||.:::...||......:.:.
Human    11 FALNLFKHLAK------ASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNEVGANAVT 69

  Fly    76 ----LNFGEFWRTSCNY------------------GDR-----------------GPVLKSVNRL 101
                .||     |||.:                  .|:                 ..:|:|||:|
Human    70 PMTPENF-----TSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGNYLLESVNKL 129

  Fly   102 YVNDSLELLTEFNEIAVDFFQSKAEATRFAD-SEGATQLINDWVEQETEHKITNLLQSDAVNNET 165
            :...|.....|:..:...::.|:.:|..|.: :|.|.:.||.||:.:|:.||.|||...:|:.:|
Human   130 FGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGKIPNLLPEGSVDGDT 194

  Fly   166 SALLINVLYFKGKWQKPFMPETTSIDHFHVDRDTHVQVNMMYQEDKFRFAELPQLKARAVQLPYD 230
            ..:|:|.:||||||:.||..:...:..|.|:......|.|||..:|.....:..|||:.::|||
Human   195 RMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREKLNIGYIEDLKAQILELPY- 258

  Fly   231 YSNIHMLILLPNEV----NGLQELEQQ-----LNTVDLADIDAALTLQDVEIFLPRMCIEYDVDL 286
            ..::.|.:|||:|:    .||:.||.:     ||.....|   .:...:||:::|:..:|...:|
Human   259 AGDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKD---KMAEDEVEVYIPQFKLEEHYEL 320

  Fly   287 KQVLNQLGITEVFS-DKAKLDGLFTSQSGQKISAARHRGYIDVNEAGSEAAAVSFMKIVPMMLNM 350
            :.:|..:|:.:.|: .:|...|: :.::...:|...|:..:||||.|:|||| ....::......
Human   321 RSILRSMGMEDAFNKGRANFSGM-SERNDLFLSEVFHQAMVDVNEEGTEAAA-GTGGVMTGRTGH 383

  Fly   351 NKKLFKADHPFVFYIRN--PQAVFFAGRFSNP 380
            ....|.|||||:|.|.:  ...:.|.||||:|
Human   384 GGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dc	NP_001246154.1	SERPIN	7..377	CDD:238101	114/417 (27%)
SERPINB2	NP_001137290.1	PAI-2	4..415	CDD:239013	117/420 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	1	1.000	-	-		mtm8652
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.930