DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Dc and Spn42Dd

DIOPT Version :9

Sequence 1:	NP_001246154.1	Gene:	Spn42Dc / 35600	FlyBaseID:	FBgn0033113	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_001163067.1	Gene:	Spn42Dd / 49808	FlyBaseID:	FBgn0028988	Length:	372	Species:	Drosophila melanogaster

Alignment Length:	375	Identity:	136/375 - (36%)
Similarity:	205/375 - (54%)	Gaps:	25/375 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 ITKDALQQSKD---------PHINTVFSPASVQSALTLAFMGASGSTAEELRNGLQLGPGDRHHI 74
            :|..|.|.||:         .:.|.|.||.|:::.|::.||||.||||:||::.|.|...|:..:
  Fly    10 VTSVACQTSKEIYQLLSKSHTNQNLVVSPVSIETILSMVFMGAEGSTAKELQSALGLPSEDKEAV 74

  Fly    75 ALNFGEFWRTSCNYGDRGPVLKSVNRLYVNDSLELLTEFNEIAVDFFQSKAEATRFADSEGATQL 139
            |..:|.. .......:.||:||..||:||||...|...:|....:.|:|:||:....:...|.:.
  Fly    75 AARYGAL-LNDLQGQEEGPILKLANRIYVNDQYSLNQNYNLAVREPFKSEAESISLTNGPVAAER 138

  Fly   140 INDWVEQETEHKITNLLQSDAVNNETSALLINVLYFKGKWQKPFMPETTSIDHFHVDRDTHVQVN 204
            ||.||..:|..||..::...::.::..|||:|.:||||:|:..|.|..|....|.|..:..|.|.
  Fly   139 INQWVLDQTSGKIKGMIDPGSMTSDVKALLVNAIYFKGQWESKFDPAKTRASTFQVTANKSVPVQ 203

  Fly   205 MMYQEDKFRFAELPQLKARAVQLPYDYSNIHMLILLPNEVNGLQELEQQLNTVDLADIDAALTLQ 269
            ||.|...||......|.|:.::|||..||:.|.|.||.||.||..||:::  |..|   ..|..:
  Fly   204 MMAQMGTFRANYFRDLDAQVIELPYLNSNLSMTIFLPREVEGLSALEEKI--VGFA---RPLVAK 263

  Fly   270 DVEIFLPRMCIEYDVDLKQVLNQLGITEVFSDKAKLDGLFTSQSGQKISAARHRGYIDVNEAGSE 334
            :|.:.||:..||:..:||:.|.:|||.|:|:||:.|.|||..:||.|:|...|:.:::|||.|:|
  Fly   264 EVYLKLPKFKIEFRDELKETLEKLGIRELFTDKSDLSGLFADKSGGKVSQVSHKAFLEVNEEGAE 328

  Fly   335 AAAVSFMKIVPMMLNMNKKLFK----ADHPFVFYIRNPQAVFFAGRFSNP 380
            ||..:.:.:.      |:..|.    |||||.|.||:...::|.||..:|
  Fly   329 AAGATSVAVT------NRAGFSTFLMADHPFAFVIRDANTIYFQGRVVSP 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dc	NP_001246154.1	SERPIN	7..377	CDD:238101	134/370 (36%)
Spn42Dd	NP_001163067.1	SERPIN	16..369	CDD:238101	132/364 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446390
Domainoid	1	1.000	172	1.000	Domainoid score	I1138
eggNOG	1	0.900	-	-		E33208_3BBFJ
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	172	1.000	Inparanoid score	I1521
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D140751at6656
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	1	1.000	-	-		mtm8430
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
	10	9.900