DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Dc and serpinb1l1

DIOPT Version :9

Sequence 1:	NP_001246154.1	Gene:	Spn42Dc / 35600	FlyBaseID:	FBgn0033113	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_001009892.2	Gene:	serpinb1l1 / 494155	ZFINID:	ZDB-GENE-040715-5	Length:	384	Species:	Danio rerio

Alignment Length:	395	Identity:	128/395 - (32%)
Similarity:	210/395 - (53%)	Gaps:	26/395 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSEPQEGRNQFARNLIDVITKDALQQSKDPHINTVFSPASVQSALTLAFMGASGSTAEELRNGLQ 65
            |........||:.||...|:      ..:...|..:||.|:.|||.:..:||.|:||:::..  .
Zfish     1 MESLSAANTQFSLNLFKKIS------GGNASGNVFYSPVSISSALAMVSLGAKGNTADQMFK--V 57

  Fly    66 LGPGDRHH-----IALNFGEFWRTSCNYGDRGPVLKSVNRLYVNDSLELLTEFNEIAVDFFQSKA 125
            ||...:.|     |..||.:| .:..|..:...||...||||...:.:|:.:|......::.:..
Zfish    58 LGFNSQAHQPVEQIHSNFKKF-MSELNKPEAPYVLSLANRLYGEQTYQLIEKFLNDTKRYYDAGL 121

  Fly   126 EATRFAD-SEGATQLINDWVEQETEHKITNLLQSDAVNNETSALLINVLYFKGKWQKPFMPETTS 189
            |...|.: ||.|...||.|||:.|:.||.:||.|.|::..|..:|:|.:||||.|::.|..|.|.
Zfish   122 EKVDFINKSEDARVNINTWVEKNTQEKIKDLLPSGAIDAMTRLVLVNAIYFKGNWEEKFPKEATR 186

  Fly   190 IDHFHVDRDTHVQVNMMYQEDKFRFAELPQLKARAVQLPYDYSNIHMLILLPNEV----NGLQEL 250
            ...|.::::....|.||:|:.:|....:.::|:..::|||...|:.|||:||:|:    .|||:|
Zfish   187 DGVFRLNKNQTKPVKMMHQKAEFPSGYIEEMKSHVLELPYAGKNLSMLIILPDEIEDETTGLQKL 251

  Fly   251 EQQLNTVDLAD--IDAALTLQDVEIFLPRMCIEYDVDLKQVLNQLGITEVFS-DKAKLDGLFTSQ 312
            |:.|....|.:  ....:..::|::.||:...|...|:|.:|..:|:.:||. .|..|.|: :|.
Zfish   252 ERALTYEKLMEWTKPEVMHQREVQVSLPKFKTEQTYDMKSLLVSMGMEDVFDPQKVNLTGM-SSS 315

  Fly   313 SGQKISAARHRGYIDVNEAGSEAAAVSFMKIVPMMLNMNKKLFKADHPFVFYIR-NP-QAVFFAG 375
            :...:|.|.|:.:::|||.|:||||.: ..|..:|..:....|.|||||:|:|| || :::.|.|
Zfish   316 NDLVLSKAIHKAFVEVNEEGTEAAAAT-AAIEKLMCYIPPLSFNADHPFLFFIRHNPTKSILFYG 379

  Fly   376 RFSNP 380
            |..:|
Zfish   380 RLCSP 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dc	NP_001246154.1	SERPIN	7..377	CDD:238101	125/384 (33%)
serpinb1l1	NP_001009892.2	PAI-2	4..384	CDD:239013	126/390 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	218	1.000	Domainoid score	I2586
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	1	1.000	-	-		mtm8430
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.830