DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Dc and Serpina11

DIOPT Version :9

Sequence 1:	NP_001246154.1	Gene:	Spn42Dc / 35600	FlyBaseID:	FBgn0033113	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_001008776.1	Gene:	Serpina11 / 362774	RGDID:	1359239	Length:	462	Species:	Rattus norvegicus

Alignment Length:	452	Identity:	102/452 - (22%)
Similarity:	188/452 - (41%)	Gaps:	88/452 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSEPQEGRNQFA------RNLIDVITKDAL----QQSKDPHINTVFSPASVQSALTLAFMGASGS 55
            :..||...:|..      ..:...||..||    |.:::...|.:|||.|:.|.:.|..:||...
  Rat    30 LGAPQPASHQSLEPAPAYHKVTPTITNFALRLYKQLAEEIPGNILFSPVSLSSTVALLSLGAHAD 94

  Fly    56 TAEELRNGLQLGPGDRHHIALNFGEFWRTSCNYGDRGPV-----------LKSVNRLYVNDSLEL 109
            |..::...|          ..|..|......:.|.:..:           ||..:.|:::..|:.
  Rat    95 TQAQILQSL----------GFNLTETPAADIHRGFQSLLHTLDLPSPKLELKLGHSLFLDRQLKP 149

  Fly   110 LTEFNEIAVDFFQSKAEATRFADSEGATQLINDWVEQETEHKITNLLQSDAVNNETSALLINVLY 174
            ...|.:.|.:.:.:.|.:..|.::....|.|||.|.::|..::...|..  .:.:|..:|:|.::
  Rat   150 QQRFLDSAKELYGALAFSANFTEAAATGQQINDLVRKQTYGQVVGCLPE--FDRDTLMVLLNYIF 212

  Fly   175 FKGKWQKPF-MPETTSIDHFHVDRDTHVQVNMMYQEDKFRFAELPQLKARAVQLPYDYSNIHMLI 238
            ||.||:.|| ..:|...:.|.||:...:::.||.|::..||  |...:|....|..:||...:|:
  Rat   213 FKAKWKHPFDRYQTRKQESFFVDQRLQLRIPMMRQKEMHRF--LYDQEASCTVLQIEYSGTALLL 275

  Fly   239 LLPNEVNGLQELE----------------------------------------QQLNTVDLADID 263
            |:..:...:|::|                                        .::..:.|..:.
  Rat   276 LVLPDPGKMQQVEAALQPETLRRWGQRFLPRKAQAGGAGNGGLHWDRVNEFPQNRVGKLSLKHLQ 340

  Fly   264 AALTLQDVEIFLPRMCIEYDVDLKQVLNQLGITEVFSDKAKLDGLFTSQSGQKISAARHRGYIDV 328
            ...|...:::.|||..:....:|:::|..:|::.:|..:|.|.|:. .|..:.:|...|:..:|:
  Rat   341 MTQTWSLLDLHLPRFSVSATYNLEEILPLVGLSSLFDVEADLSGIM-GQLNKTVSRVSHKAVVDM 404

  Fly   329 NEAGSEAAAVSFMKIVPMMLNMNKKLFKADH-----PFVFYI--RNPQAVFFAGRFSNPKSG 383
            ||.|:||||.|.:...|..|||.    .|.|     ||:..:  ...|::.|.|:..||.:|
  Rat   405 NEKGTEAAAASGLLSQPPSLNMT----SAPHAHFNRPFLLLLWEVTTQSLLFLGKVVNPAAG 462

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dc	NP_001246154.1	SERPIN	7..377	CDD:238101	97/438 (22%)
Serpina11	NP_001008776.1	alpha-1-antitrypsin_like	53..456	CDD:239011	96/421 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.010