DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Dc and serpind1

DIOPT Version :9

Sequence 1:	NP_001246154.1	Gene:	Spn42Dc / 35600	FlyBaseID:	FBgn0033113	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_878300.1	Gene:	serpind1 / 359841	ZFINID:	ZDB-GENE-030711-2	Length:	507	Species:	Danio rerio

Alignment Length:	422	Identity:	112/422 - (26%)
Similarity:	199/422 - (47%)	Gaps:	71/422 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 EPQEGRNQFARNL-----------IDVIT-----------KDALQQSKDPHINTVFSPASVQSAL 45
            ||.:.:.:.||.|           |:|:.           ::.|.|:.    |.:.:|..:..|:
Zfish   110 EPSDPKIRRARLLRLFHGQTRLQRINVVNARFGFRLYRKLRNRLNQTD----NILLAPVGISIAM 170

  Fly    46 TLAFMGASGSTAEELRNGLQLGPGDRHHIALNFGEFWRTSCNYGDR------------------G 92
            .:..:|...:|.|:|..            .:.|.||...|.:|.:.                  |
Zfish   171 GMMGLGVGPNTQEQLFQ------------TVGFAEFVNASNHYDNSTVHKLFRKLTHRLFRRNFG 223

  Fly    93 PVLKSVNRLYVNDSLELLTEFNEIAVDFFQSKAEATRFADSEGATQLINDWVEQETEHKITNLLQ 157
            ..|:|||.|||..::::...|...|..::.::.::..|||.....: .|..:::.|:..|...|:
Zfish   224 YTLRSVNDLYVKRNVQIQDSFRADAKTYYFAEPQSVDFADPAFLVK-ANQRIQKITKGLIKEPLK 287

  Fly   158 SDAVNNETSALLINVLYFKGKWQKPFMPETTSIDHFHVDRDTHVQVNMMYQEDKFRFAELPQLKA 222
            |  |:...:.:|:|.|||||.|::.|..|.|....|.|:....|:|.||..:..:..|...:|..
Zfish   288 S--VDPNMAVMLLNYLYFKGTWEQKFPKELTHHRQFRVNEKKQVRVLMMQNKGSYLAAADHELNC 350

  Fly   223 RAVQLPYDYSNIHMLILLPNEVNGLQELEQQLNTVDLADIDAALTLQDVEIFLPRMCIEYDVDLK 287
            ..:|||| ..||.|||.:|.:::|::.|||:::...:....:.:|.:..|:..||..:|.:.||.
Zfish   351 DILQLPY-AGNISMLIAVPQKLSGMRSLEQEISPTLVNKWLSNMTNRTREVVFPRFKLEQNYDLI 414

  Fly   288 QVLNQLGITEVFSDKAKLDGLFTSQSGQK--ISAARHRGYIDVNEAGSEAAAVSFMKIVPMMLNM 350
            :.|.::|:|::|::|    |.|:..:.:|  |:..:|:|.|.|||.|:||||::.:..:|:   .
Zfish   415 EHLKEMGMTDIFTEK----GDFSPMTSEKVIINWFKHQGSITVNEEGTEAAAMTHIGFMPL---S 472

  Fly   351 NKKLFKADHPFVF--YIRNPQAVFFAGRFSNP 380
            .:..|..|.||:|  |......|.|.||..:|
Zfish   473 TQTRFIVDRPFLFLIYEHRTGCVVFMGRVVDP 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dc	NP_001246154.1	SERPIN	7..377	CDD:238101	108/413 (26%)
serpind1	NP_878300.1	HCII	61..505	CDD:239002	112/422 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	4.020